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目的：测定１６例前列腺癌（ＰＣａ）和３３例前列腺增生（ＢＰＨ）患者血清前列腺特异性抗原（ＰＳＡ），前列腺特异抗原密度（ＰＳＡＤ）及游离前列腺特异抗原（ｆＰＳＡ）。方法：采用放射免疫法。结果：显示ＰＳＡＤ对ＰＣａ诊断敏感度高而特异阳性预测值低，而ＰＳＡＤ及ｆＰＳＡ／ｔＰＳＡ比值（即参数百分率）是提高ＰＣａ和ＢＰＨ鉴别诊断阳性率的一种较好指标。结论：本实验结果在实际临床应用中有重要意义。
Objective: To determine the serum PSA, PSAD and fPSA in 16 patients with prostate cancer (PCa) and 33 patients with benign prostatic hyperplasia (BPH). Methods: Radioimmunoassay Results: PSAD showed a high sensitivity for PCa and a low positive predictive value. The ratio of PSAD and fPSA / tPSA (ie, percentage of parameters) was a good indicator for increasing the positive rate of differential diagnosis between PCa and BPH. Conclusion: The experimental results in the actual clinical application of great significance.