过去的研究表明 ,作为新型半天然钙调蛋白拮抗剂的小檗胺衍生物 (O- 4- Ethoxyl-Butyl- Berbamine) EBB,无论是在体内 ,还是在体外都具有显著的强抑制肿瘤细胞和对正常细胞毒性小的特点 .但就 EBB使细胞死亡的方式未进行深入的研究 ,本文就 EBB诱导人肺癌细胞 (PG)进行了初探 ,从电泳图谱出现的 6 0 0 bp～ 80 0 bp之间的一条带说明 ,EBB诱导 PG-cell凋亡且诱导凋亡的过程中 ,还存在其他的生化反应 ,有待人们进一步的研究与探讨 . Past studies have shown that O-4-Ethoxyl-Butyl-Berbamine EBB, a novel semi-natural calmodulin antagonist, has potent and strong inhibition of tumor cells both in vivo and in vitro. The characteristics of normal cells are less toxic. However, there is no in-depth study on the ways in which EBB causes cell death. This article has conducted a preliminary study on the EGB-induced human lung cancer cells (PG), which are from 600 bp to 800 bp. One band indicates that there are other biochemical reactions in the process of apoptosis induced by EBB and the induction of apoptosis in EBB, which needs to be further studied and discussed.