结核病是造成人类死亡最多的疾病之一。严重危害患者本人生命健康、使无数家庭陷于贫困交加的绝境,也给社会经济带来沉重的负担。药物预防是对已感染结核菌的人群,投予抗结核药物预防结核病的发病。由于HIV感染与AIDS病的流行,HIV/MTB双重感染的人数急剧上升,疫情出现回升,并发生了耐多药结核病暴发流行,严峻的结核病态势促使药物预防再度引起人们的重视[1]。抗结核药物的出现,开创了结核病的化疗时 Tuberculosis is one of the diseases that cause the most human deaths. Seriously endangering the patient’s own life and health, leaving countless families trapped in poverty and putting a heavy burden on the social economy. Drug prevention is already infected with tuberculosis in the population, the administration of anti-TB drugs to prevent the incidence of tuberculosis. Due to the prevalence of HIV infection and AIDS, the number of people infected with HIV / MTB has risen sharply, the epidemic has risen, and an outbreak of MDR-TB has occurred. The severe TB situation has prompted drug prevention again to attract attention [1]. The emergence of anti-TB drugs, creating a TB chemotherapy