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目的研究分析2型糖尿病住院患者体位性低血压(OH)发生率及危险因素。方法对248例2型糖尿病患者进行调查,并测量患者坐位、卧位和立位不同时间血压变化,检测相关生化指标及对体位性低血压患者及非体位性低血压患者进行比较。结果 2型糖尿病患者体位性低血压发生率为34.3%。经多因素Logistic逐步回归分析,合并体位性低血压的风险与糖尿病肾病[OR=1.068,95%CI=(1.024,1.112)]、合并高血压[OR=1.045,95%CI=(1.017,1.165)]、糖化血红蛋白水平[OR=1.223,95%CI=(1.103,1.427)]、卧位收缩压[OR=1.071,95%CI=(1.024,1.286)]呈现正相关(P<0.05)。结论 2型糖尿病住院患者体位性低血压发生率较高,糖尿病肾病、合并高血压、糖化血红蛋白水平以及卧位收缩压升高是体位性低血压发生的危险因素,通过有效的控制能够有效的降低体位性低血压的发生。
Objective To study the incidence and risk factors of orthostatic hypotension (OH) in hospitalized type 2 diabetic patients. Methods A total of 248 patients with type 2 diabetes mellitus were investigated. The changes of blood pressure in sitting, lying position and standing position were measured. The biochemical parameters were measured and the patients with orthostatic hypotension and non-orthostatic hypotension were compared. Results The incidence of orthostatic hypotension in type 2 diabetic patients was 34.3%. Multivariate Logistic regression analysis showed that the risk of orthostatic hypotension was associated with diabetic nephropathy (OR = 1.068, 95% CI = (1.024,1.112)], and hypertension with OR = 1.045,95% CI (1.017,1.165 ), HbA1c (OR = 1.223, 95% CI = (1.103,1.427)], supine systolic pressure [OR = 1.071,95% CI = (1.024,1.286)]. Conclusions The incidence of orthostatic hypotension is higher in inpatients with type 2 diabetes. Diabetic nephropathy, combined hypertension, glycosylated hemoglobin level and elevated systolic blood pressure are the risk factors of orthostatic hypotension. Effective control can effectively reduce the incidence of orthostatic hypotension Postural hypotension.