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随着阿苯达唑和甲苯达唑在驱肠道线虫中的广泛应用,有关药物抗性的问题已渐渐引起人们的关注。作者通过对既往研究的比较分析,观察上述3种药物对蛔虫、鞭虫和钩虫的作用。以治愈率(CR)和减卵率(ERR)作为药物疗效的判断指标。结果发现:用WHO推荐的治疗剂量,阿苯达唑和甲苯达唑驱蛔虫的效果都很好,平均CR为95％—97％、ERR为99％—100％,且不同治疗剂量对疗效影响不大。但若用于驱鞭虫和钩虫,疗效降
With the widespread use of albendazole and mebendazole in carnovorous nematodes, the issue of drug resistance has drawn increasing attention. The author through the comparative analysis of previous studies to observe the above three drugs on roundworm, whipworm and hookworm effect. To cure rate (CR) and egg reduction rate (ERR) as indicators of drug efficacy. The results showed that the therapeutic doses recommended by the WHO, albendazole and mebendazole roundworm effect are good, with an average CR 95% -97%, ERR 99% -100%, and the effect of different therapeutic doses on the efficacy Not big. However, if used to drive whipworm and hookworm, curative effect decreased