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棉花枯萎病首先于１８９１年在美国亚拉巴马州发现，现在除澳大利亚外几乎遍及世界各产棉国。抗病机制是由于物理阻碍或化学抑菌作用所致，或者是两者同时存在的结果，但化学抑菌起着主导作用。一般认为，抗棉花枯萎病性遗传是多基因控制的，或是１个主基因和多个微效基因所控制，或者由２个显性基因和１个抑制基因控制；也有认为是受显性单基因控制的。
Cotton blight was first discovered in Alabama in 1891 in the United States and is now almost everywhere in the world except Australia. Disease resistance mechanism is due to physical obstruction or chemical antibacterial effect, or a combination of the two, but chemical antibacterial plays a leading role. It is generally believed that resistance to Fusarium wilt disease is controlled by multiple genes, controlled by one major gene and multiple minor genes or controlled by two dominant genes and one suppressor gene, and also considered dominant Single gene control.