目的:研究阿司匹林(Asp)与硝苯地平(Nif)并用对麻醉犬血液动力学的影响。方法:TTI,LVWI,MAP,TPVR,FBF,LVSP,dp/dt_(max),LVEDP,HR,均同步记录于多道生理记录仪及电磁流量计上。结果:Asp5,10mg·kg~(-1)iv对 麻醉犬血液动力学各项指标均无明显影响。Nif15μg·kg~(-1) iv可使TTI,MAP,TPVR显著下降,FBF明显提高,对LVSP,dp/dt_(max),HR,CI无明显影响。Asp 5mg·kg~(-1)与Nif 15μg·kg~(-1)并用与Nif单用结果相似。结论:Asp不影响Nif改善心血管功能的作用。 Objective: To study the effects of aspirin (Nif) combined with Asp on hemodynamics in anesthetized dogs. Methods: TTI, LVWI, MAP, TPVR, FBF, LVSP, dp / dt max, LVEDP and HR were simultaneously recorded on multi-channel physiology recorder and electromagnetic flowmeter. Results: Asp5 and 10 mg · kg ~ (-1) iv had no significant effect on all indexes of haemodynamics in anesthetized dogs. Nif15μg · kg -1 iv could significantly decrease TTI, MAP and TPVR, improve FBF, and have no significant effect on LVSP, dp / dt max, HR and CI. Asp 5 mg · kg -1 and Nif 15 μg · kg -1 were similar to Nif alone. Conclusion: Asp does not affect the role of Nif in improving cardiovascular function.