观察了用重组人粒细胞—巨噬细胞集落刺激因子（ｒＨｕＧＭ—ＣＳＦ）治疗儿童急淋化疗后白细胞和血小板减少的临床效果。选择住院化疗患儿，用ｒＨｕＧＭ—ＣＳＦ皮下注射，每次１５０μｇ，每日１次，连续２～３次。用药后取静脉血计数白细胞和血小板。结果：６例急淋患儿，用药后白细胞均增加，增幅＞０５×１０９／Ｌ４例，＞０１×１０９／Ｌ２例，６例中有５例血小板增幅＞２０×１０９／Ｌ。提示用ｒＨｕＧＭ—ＣＳＤ治疗小儿急淋化疗后白细胞和血小板减少有效，值得深入探讨 The clinical effect of treatment of leukocytopenia and thrombocytopenia after acute leaching chemotherapy in children with recombinant human granulocyte-macrophage colony-stimulating factor (rHuGM-CSF) was observed. The children who were hospitalized for chemotherapy were injected subcutaneously with rHuGM-CSF 150 μg each time, once daily for 2 to 3 consecutive sessions. Venous blood and leukocytes and platelets were taken after administration. RESULTS: In 6 children with acute leucorrhea, leukocytes were increased after treatment, with an increase of >05×109/L4, >01×109/L2, and 5 cases of platelet increase>20×109/L in 6 cases. . It is suggested that the use of rHuGM-CSD in the treatment of leukocyte and thrombocytopenia after acute leukotherapy in children is effective and worthy of in-depth study