在唐氏综合征新生儿群体中,存在一种独特的血液学现象,即患儿出生时骨髓、外周血中出现大量幼稚巨核细胞,临床与急性巨核细胞白血病十分相似,不同的是这种幼稚巨核细胞可以自发消失。发生于唐氏综合征患儿中的这种现象又称为一过性白血病,此现象有两大特点:一是发生的时间窗较 In the neonatal population of Down Syndrome, there is a unique hematology phenomenon, namely, the birth of bone marrow in children, there are a large number of naive megakaryocytes in peripheral blood, clinical and acute megakaryocyte leukemia is very similar, the difference is this naive Megakaryocytes can disappear spontaneously. This phenomenon occurs in children with Down Syndrome, also known as transient leukemia, this phenomenon has two major characteristics: First, the occurrence of the time window than