论文部分内容阅读
目的观察苯巴比妥预防新生儿高胆红素血症的效果。方法以出生后 1天内住院的 180例新生儿为研究对象 ,预防组于生后 2 4小时内给予苯巴比妥 5 mg/(kg· d) ,每日 2次口服 ,疗程 3天 ;对照组不用苯巴比妥。用经皮胆红素测定仪测定胆红素 ,比较两组胆红素的变化。结果预防组总胆红素均值明显低于对照组 ,预防组高胆红素血症的发病率为 2 7.8% ,明显低于对照组的 68.9%(P<0 .0 1)。结论生后预防性口服苯巴比妥可降低新生儿胆红素浓度和新生儿高胆红素血症的发病率
Objective To observe the effect of phenobarbital in preventing neonatal hyperbilirubinemia. Methods One hundred and eighty newborns hospitalized within one day after birth were enrolled in this study. The prophylaxis group was given phenobarbital 5 mg / (kg · d) within 24 hours of birth, twice daily for 3 days. The control group The group did not use phenobarbital. Percutaneous bilirubin determination of bilirubin, bilirubin changes between the two groups were compared. Results The mean total bilirubin in the prevention group was significantly lower than that in the control group. The incidence of hyperbilirubinemia in the prevention group was 2 7.8%, which was significantly lower than that in the control group (68.9%, P 0. 01). CONCLUSIONS: Preventive oral phenobarbital may reduce the neonatal bilirubin concentration and the incidence of neonatal hyperbilirubinemia