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[学位论文] 作者：胡言石,,
来源：天津医科大学 年份：2016
研究目的:作为一种常见的神经退行性疾病,帕金森病不仅严重影响病人及家人的生活质量,同时给社会造成了巨大的经济负担。尽管已经有很多研究致力于揭示帕金森病的致病机制,对...
[会议论文] 作者：胡言石,潘振华,胡莹,王举,
来源：第七届全国生物信息学与系统生物学学术大会 年份：2016
Parkinsons disease (PD) is a major neurodegenerative disease influenced by both genetic and environmental factors.Although previous studies have provided insights into the significant impact of geneti...
Identifying the Enriched Biological Pathways in Genes Related to Nicotine Dependence via a Network-b
[会议论文] 作者：方忠海,杨一晨,胡莹,胡言石,
来源：第七届全国生物信息学与系统生物学学术大会 年份：2016
Pathway enrichment algorithms are applied to detect biological pathways significantly related to a given set of genes associated with a specific disease or phenotype,experimental biology conditions.In...
Uncovering the common pathogenesis in neurodegenerative and psychiatric disorder via network approac
[会议论文] 作者：胡莹,胡言石,杨一晨,方忠海,王举,
来源：第七届全国生物信息学与系统生物学学术大会 年份：2016
Both neurodegenerative and psychiatric disorder are common and severe CNS diseases with symptom similarity and comorbidity;however,the underlying biological processes across these disorders remain lar...
[会议论文] 作者：胡言石,范锐,李霞,刘孟,刘新华,伊现富,张涛,王举,
来源：第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 年份：2014
Background: Alzheimers disease (AD) and Parkinsons diseases (PD) are major neurodegenerative diseases.Previous studies have provided insights into the impacts of genetic factors on AD and PD, and some...
[会议论文] 作者：范锐,刘孟,李霞,刘新华,胡言石,胡莹,伊先富,张涛,王举,
来源：第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 年份：2014
Background: Nicotinic acetylcholine receptors (nAChRs), the ligand-gated ion channels in the plasma of certain neurons that signal for synaptic transmission upon a chemical stimulus like acetylcholine...
[会议论文] 作者：刘孟,刘新华,李霞,范锐,胡言石,胡莹,伊现富,张涛,王举,
来源：第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 年份：2014
Background: Cigarette smoking is a main cause of preventable diseases and premature death worldwide.Nicotine is the major psychoactive component of tobacco...
[会议论文] 作者：李霞,刘孟,刘新华,范锐,胡言石,胡莹,伊现富,张涛,王举,
来源：第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 年份：2014
Background: MicroRNAs (miRNAs) play important roles in post-transcription by repressing translation or causing mRNA degradation.A single miRNA may be involved in the expression regulation of a large n...
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