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[期刊论文] 作者:Andrew C.J.Huang,,
来源:Neural Regeneration Research 年份:2012
A rat model of Parkinson’s disease was induced by injecting lactacystin stereotaxically into the left mesencephalic ventral tegmental area and substantia nigra...
Effects of serum containing natural cerebrolysin on glucose-regulated protein 78 and CCAAT enhancer-
[期刊论文] 作者:Andrew C.J.Huang O,,
来源:Neural Regeneration Research 年份:2009
BACKGROUND:Glucose-regulated protein 78(GRP78),a marker of endoplasmic reticulum stress,can prolong cell survival.Alternatively,CCAAT enhancer-binding protein h...
[期刊论文] 作者:吴正治,Andrew C.J.Huang,高小威,朱庆伟,李,
来源:世界中西医结合杂志 年份:2009
目的探讨中药安颤灵对帕金森病(PD)大鼠模型泛素-蛋白酶体系统(UPS)功能的影响。方法采用lactacystin立体定向注射入大鼠左侧黑质致密部和黑质纹状体通路,建立PD大鼠模型。经行为......
Effect of Tiantai No.1 (天泰1号) on β-Amyloid-induced Neurotoxicity and NF-κ B and cAMP Responsive Elem
[期刊论文] 作者:吴正治,Andrew C.J.Huang,Jean de Vellis,李映红,,
来源:Chinese Journal of Integrative Medicine 年份:2008
Objective:To investigate the effect and molecular mechanism of Tiantai No.1(天泰1号),a compound Chinese herbal preparation,for the prevention and reduction of n...
[会议论文] 作者:吴正治,Andrew C.J.Huang,李桂云,李映红,李明,陈蔓茵,
来源:首届国际中西医结合内分泌代谢病学术大会暨糖尿病论坛 年份:2008
本文通过实验对糖胰敏对游离脂肪酸诱导胰岛细胞凋亡的影响进行了分析讨论,本实验以原代培养大鼠胰岛细胞为研究对象,结果显示,FFA长期作用于胰岛细胞,使胰岛细胞的胰岛素分泌功能明显降低,凋亡率显著增高。中药糖胰敏含药血清能够改善FFA对胰岛细胞功能的损伤作用,使......
[期刊论文] 作者:李映红,吴正治,Andrew C.J.Huang,李明,张晓丽,杨敏,陈蔓茵,,
来源:世界中西医结合杂志 年份:2009
目的探讨天然脑活素对复制性衰老人胚肺二倍体成纤维细胞(MRC-5)端粒酶活性的影响,以阐明其延缓衰老的作用及分子机制。方法镜下观察细胞形态变化,绘制细胞生长曲线,MTT法检...
Endoplasmic Reticulum Stress Induced by Tunicamycin and Antagonistic Effect of Tiantai No.1(天泰1号) on
[期刊论文] 作者:吴正治,李映红,Andrew C.J.Huang,李明,张晓丽,王济国,杨敏,陈嫚茵,,
来源:Chinese Journal of Integrative Medicine 年份:2010
Objective:Changes of the internal and external cellular environments can induce calcium homeostasis disorder and unfolded protein aggregation in the endoplasmic...
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