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[会议论文] 作者:Chan Shan,Jing Lin,Jin-Qiang Hou,Jia-Heng Tan,Tian-Miao Ou,Zhi-Shu Huang,
来源:2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份:2015
c-MYC is a classical G-quadruplex-relating gene that is considered as an effective target for anticancer therapy [1].The transcriptional factor NM23-H2 coul...
Small-Molecule-Induced Transcription Repression through Interfering with NM23-H2 Binding to G-quadru
[会议论文] 作者:Jing Lin,Chan Shan,Tian-Miao Ou,Jin-Qiang Hou,Shuo-bin Chen,Jia-Heng Tan,Lian-Quan Gu,Zhi-Shu Huang,
来源:全国药物化学学术会议暨第四届中英药物化学学术会议 年份:2013
NM23-H2 protein is identified as a transcriptional factor of the important oncogene c-myc,that can bind specifically to defined DNA sequences to promote gene transcription.However,due to its role in t...
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