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Neutron and ultrahigh resolution X-ray crystallography unravels the catalytic mechanism of dihydrofo
[会议论文] 作者:Qun Wan,Brad Bennett,Chris Dealwis,Andrey Kovalesky,Paul Langan,Mark Wilson,
来源:8th IUPAP International Conference on Biological Physics(第八届 年份:2014
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Unraveling the catalytic mechanism of ecDHFR using neutron and ultrahigh-resolution x-ray diffractio
[会议论文] 作者:Qun Wan,Andrey Kovalevsky,Paul Langan,Mark Wilson,Brad Bennett,Chris Dealwis,
来源:中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 年份:2014
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Neutron and ultrahigh resolution X-ray crystallography unravels the catalytic mechanism of dihydrofo
[会议论文] 作者:Qun Wan,Brad Bennett,Andrey Kovalesky,Paul Langan,Mark Wilson,Chris Dealwis,
来源:8th IUPAP International Conference on Biological Physics(第八届 年份:2014
Dihydrofolate reductase (DHFR) is a household enzyme that is responsible for the NADPH-dependent conversion of dihydrofolate (DHF) to tetrahydrofolate (THF).The mechanism involves proton donation at N...
Unraveling the catalytic mechanism of ecDHFR using neutron and ultrahigh-resolution x-ray diffractio
[会议论文] 作者:Qun Wan,Andrey Kovalevsky,Mark Wilson,Brad Bennett,Paul Langan,Chris Dealwis,
来源:中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 年份:2014
Dihydrofolate reductase (DHFR) is a household enzyme involved in many biosyntheticpathways including purine synthesis.The enzymatic reaction involves converting dihydrofolate(DHF) to tetrahydrofolate...
Toward resolving the catalytic mechanism of dihydrofolate reductase using neutron and ultrahigh-reso
[会议论文] 作者:Qun Wan,Brad C.Bennett,Mark A.Wilson,Andrey Kovalevsky,Paul Langan,Elizabeth E.Howell,Chris Dealwis,
来源:第十二届全国酶学学术讨论会 年份:2015
Dihydrofolate reductase(DHFR)catalyzes the NADPH-dependent reduction of dihydrofolate(DHF)to tetrahydrofolate(THF)...
Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydr
[会议论文] 作者:Qun Wan,Brad C.Bennett,Mark A.Wilson,Andrey Kovalevsky,Paul Langan,Elizabeth E.Howell,Chris Dealwis,
来源:第三届全国中子散射会议暨国际中子源多学科应用研讨会 年份:2015
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