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[期刊论文] 作者：Wenjing Cheng,Yinggang Sun,Qin Wu,Kokwin Ooi,Yi Feng,Chunmei Xia,Danian Zhu,
来源：神经科学通报（英文版） 年份：2021
The present study was designed to investigate the mechanisms by which P2X7 receptors(P2X7Rs)mediate the activation of vasopressinergic neurons thereby increasin...
Microglia-Derived NLRP3 Activation Mediates the Pressor Effect of Prorenin in the Rostral Ventrolate
[期刊论文] 作者：Zhang,Kokwin Ooi,Xuehai Wu,Jiaxiang Wu,Jian Cai,Yinggang Sun,Jijiang Wang,Danian Zhu,Fuxue Chen,Chunmei Xia,
来源：神经科学通报（英文版） 年份：2020
Increased microglial activation and neuroinflammation within autonomic brain regions such as the rostral ventrolateral medulla (RVLM) have been implicated in stress-induced hypertension (SIH).Prorenin,a member of the brain renin-angiotensin......
Design,Synthesis and Biological Evaluation of Octahydrocyclopenta[b]pyrrole-2-Carbonitrile Derivativ
[会议论文] 作者：Xun Ji,Linxiang Zhao,Hualiang Jiang,Hong Liu,Mingbo Su,Jiang Wang,Chunmei Xia,Lei Zhang,Tiancheng Dong,
来源：第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份：2012
A novel series of β-amino pyrrole-2-carbonitrile derivatives was designed and synthesized based on the three-dimensional binding modes of Denagliptin1 and Sitagliptin2.Using the two important predomin...
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