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Assembly of Thermodynamically and Chemically Stable RNA Nanoparticles Escorting Mirna, Sirna and Dru
[会议论文] 作者：Dan Shu,Yi Shu,Farzin Haque,Peixuan Guo,
来源：International Conference on Nanoscience & Technology,China 2 年份：2013
One of the advantages of RNA Nanotechnology is the feasibility to construct therapeutic particles carrying multiple therapeutics with defined structure and stoichiometry.Herein, we report the construc...
Fabrication of Versatile RNA Nanoparticles for Speclflc Tumor Targeting without Accumulation in Norm
[会议论文] 作者：Yi Shu,Farzin Haque,Dan Shu,Peixuan Guo,
来源：International Conference on Nanoscience & Technology,China 2 年份：2013
Due to structural flexibility, RNase sensitivity, and serum instability, the construction of RNA nanoparticles with concrete shapes for in vivo application remains challenging.Here we report the const...
Crystal Structure of 3WJ Core Revealing Divalent Ion-promoted Thermostability and Assembly of the Ph
[会议论文] 作者：Hui Zhang,James A.Endrizzi,Yi Shu,Farzin Haque,Young-In Chi,Peixuan Guo,
来源：International Conference on Nanoscience & Technology,China 2 年份：2013
Bacteriophage phi29 DNA packaging motor, one of the strongest biological motors constructed to date, is geared by a packaging RNA (pRNA) ring.The special properties of phi29 pRNA have led to the devel...
[会议论文] 作者：Farzin Haque,Dan Shu,Yi Shu,Hui Li,Daniel Jasinski,Emil Khisamutdinov,Peixuan Guo,
来源：The 6th International Conference on Nanoscience and Technolo 年份：2015
Targeted drug delivery has been one of the most challenging aspects for cancer therapeutics.We have applied a RNA nanotechnology approach to construct multi...
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