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[期刊论文] 作者:Fawzia Bardag-Gorce,, 来源:World Journal of Gastroenterology 年份:2010
Proteasome dysfunction has been repeatedly reported in alcoholic liver disease. Ethanol metabolism endproducts affect the structure of the proteasome, and, ther...
[期刊论文] 作者:Fawzia Bardag-Gorce,, 来源:World Journal of Gastroenterology 年份:2011
氧化应力,由长期的乙醇消费产生了,是 hepatotoxicity 和肝损害的一个主要原因。由于乙醇,由 CYP2E1 的新陈代谢主要是的导出氧的自由激进分子的增加的生产在细胞质并且在线粒体...
[期刊论文] 作者:Fawzia Bardag-Gorce,, 来源:World Journal of Gastroenterology 年份:2009
Alcohol ingestion causes alteration in several cellular mechanisms, and leads to inflammation, apoptosis, immunological response defects, and fibrosis. These ph...
[期刊论文] 作者:Samuel W French,Fawzia Bardag-Gorce,Barbara A French,Joan Oliva,, 来源:World Journal of Hepatology 年份:2010
This editorial reviews the recent evidence showing that Mallory-Denk bodies(MDBs)form in hepatocytes as the result of a drug-induced shift from the 26s proteaso...
[期刊论文] 作者:Samuel W French,Joan Oliva,Barbara A French,Fawzia Bardag-Gorce,, 来源:World Journal of Gastroenterology 年份:2010
This article reviews the evidence that ties the development of hepatocellular carcinoma (HCC) to the natural immune pro-inflammatory response to chronic liver d...
[期刊论文] 作者:Joan Oliva,Jennifer Dedes,Jun Li,Samuel W French,Fawzia Bardag-Gorce, 来源:世界胃肠病学杂志(英文版) 年份:2009
AIM: To examine the effects of ethanol-induced proteasome inhibition, and the effects of proteasome inhibition in the regulation of epigenetic mechanisms. METHO...
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