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FFPM,a PDE4 inhibitor,recues cognitive dysfunction in APP/PS1 transgenic mice via cAMP/PKA/CREB/BDNF
[会议论文] 作者：GUO Hai-biao,XU Jiang-ping,
来源：第十七届全国神经精神药理学学术会议 年份：2016
OBJECTIVE In this study,we investigated the effect of FFPM,a novel PDE4 inhibitor,on learning and memory deficits as well as the underlying mechanism in APP/PS1 transgenic mouse model of Alzheimer dis...
A novel mechanism underlying the protective effect of PDE4 inhibitor against cognitive impairment:in
[期刊论文] 作者：YOU Ting-ting,GUO Hai-biao,WAN,
来源：中国药理学与毒理学杂志 年份：2017
OBJECTIVE Inhibition of phosphodiesterase 4（PDE4） improves the learning and memory abilities in Alzheimer disease animal models. The cognition-enhancing effects o...
A Novel Mechanism Underlying the Protective Effect of PDE4 Inhibitor Against Cognitive Impairment:In
[期刊论文] 作者：YOU Ting-ting,GUO Hai-biao,WANG Hai-tao,XU Jiang-ping,,
来源：神经药理学报 年份：2017
Background:Inhibition of phosphodiesterase 4(PDE4)improves the leing and memory abilities in Alzheimers disease animal models. The cognition-enhancing effects o...
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