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Metallothionein protects against doxorubicin-induced cardiac toxicity via regulation of mitochondria
[会议论文] 作者:GUO Jia-bin,LEI Lei,FANG Hai-qing,FU Ze,PENG Shuang-qing,
来源:中国药理学会第十一次全国学术会议 年份:2011
OBJECTIVE Metallothionein (MT) has been previously shown to protect against doxorubicin (DOX)-induced cardiotoxicity, but underlying mechanism still remains poorly understood.DOX induces cardiac mitoc...
[会议论文] 作者:PENG Shuang-qing,GUO Jia-bin,YUAN Hai-tao,ZHANG Ting-fen,HOU Ming-yue,ZHAO Jun,LI Jin,Paul CARMICHAEL,
来源:中国毒理学会第六届全国毒理学大会 年份:2013
Mitochondria are major sources of cellular energy and reactive oxygen species (ROS), playing fundamental roles in regulation of cell survival and death under pathological conditions.Numerous chemicals...
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