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[会议论文] 作者:Gianfranco Alpini, 来源:2017年第三届岭南国际DMPK论坛 年份:2017
Cholangiocytes are the targets of cholangiopathies, including primary sclerosing cholangitis (PSC) that are identified by dysregulation of cholangiocyte prolife...
[会议论文] 作者:Gianfranco Alpini, 来源:2017年第三届岭南国际DMPK论坛 年份:2017
[会议论文] 作者:Gianfranco Alpini, 来源:2016年第一届中国微循环周(中国病理生理学会微循环专业委员会全体会议、世界中医药学会联合会气血专业委员会全体会议、中国 年份:2016
[期刊论文] 作者:Hannah Jones,Gianfranco Alpini,Heather Francis,, 来源:Acta Pharmaceutica Sinica B 年份:2015
This review focuses on various components of bile acid signaling in relation to cholangiocytes. Their roles as targets for potential therapies for cholangiopath...
[期刊论文] 作者:Heather Francis,Shannon Glaser,Gianfranco Alpini,Gene LeSage,, 来源:World Journal of Gastroenterology 年份:2006
Cholangiocytes are exposed to high concentrations of bile acids at their apical membrane. A selective transporter for bile acids, the Apical Sodium Bile Acid Co...
[期刊论文] 作者:Shannon Glaser,Yuyan Han,Heather Francis,Gianfranco Alpini, 来源:肝胆外科与营养 年份:2014
The intrahepatic biliary epithelium is a three-dimensional tubular system lined by cholangiocytes, epithelial cells that in addition to modify ductal bile are a...
[期刊论文] 作者:Matei P Socoteanu,Frank Mott,Gianfranco Alpini,Arthur E Frankel,, 来源:World Journal of Gastroenterology 年份:2008
Cholangiocarcinoma continues to be a challenging disease to treat. Systemic therapy is used in unresectable disease, disease progression after surgery, and in t...
[期刊论文] 作者:Paolo Onori,Eugenio Gaudio,Antonio Franchitto,Gianfranco Alpini,Heather Francis,, 来源:World Journal of Gastrointestinal Pathophysiology 年份:2010
Histamine has long been known to be involved in inflammatory events.The discovery of antihistamines dates back to the first half of the 20th century when a Swis...
[期刊论文] 作者:Candace Wise,Metaneeya Pilanthananond,Benjamin F Perry,Gianfranco Alpini,Michael McNeal,Shannon S Glaser, 来源:World Journal of Gastroenterology 年份:2008
Cholangiocarcinoma is a rare cancer originating from the neoplastic transformation of the epithelial cells (i.e. cholangiocytes) that line the biliary tract. Th...
[期刊论文] 作者:Anastasia Renzi,Romina Mancinelli,Paolo Onori,Antonio Franchitto,Gianfranco Alpini,Shannon Glaser,Eugenio, 来源:肝胆外科与营养 年份:2014
Background and aims: Reduction of biliary serotonin N-acetyltransferase (AANAT) expression and melatonin administration/secretion in cholangiocytes increases bi...
[会议论文] 作者:Kelly McDaniel,Shannon Glaser,Gianfranco Alpini,Fanyin Meng,Heather Francis,Yuyan Han,Julie Venter, 来源:The 15th ICQC International Congress of Quantum Chemistry(第1 年份:2015
[会议论文] 作者:Gianfranco Alpini,Kelly McDaniel,Yuyan Han,Julie Venter,Shannon Glaser,Heather Francis,Fanyin Meng, 来源:The 15th ICQC International Congress of Quantum Chemistry(第1 年份:2015
BACKGROUND & AIMS:The biliary tree is a complex network of interconnected ducts that increase in diameter from small to large bile ducts....
[期刊论文] 作者:Glaser,Heather Francis,Sharon DeMorrow,Gene LeSage,Giammarco Fava,Marco Marzioni,Julie Venter,Gianfranco Alpini, 来源:World Journal of Gastroenterology 年份:2006
The objectives of this review are to outline the recent findings related to the morphological heterogeneity of the biliary epithelium and the heterogeneous path...
[会议论文] 作者:Kelly McDaniel,Fanyin Meng,Tami Annable,Gianfranco Alpini,Heather Francis,Shannon Glaser,Ying Wan,Julie, 来源:The 1st NI-CMI Joint Conference(第一届CMI-NI免疫学国际研讨会) 年份:2015
[会议论文] 作者:Kelly McDaniel,Ying Wan,Julie Venter,Tami Annable,Debolina Ray,Heather Francis,Shannon Glaser,Gianfranco Alpini, 来源:The 1st NI-CMI Joint Conference(第一届CMI-NI免疫学国际研讨会) 年份:2015
Background: Transcriptional factor c-myc has an important role in the regulation of many cellular programs including cellular senescence, a stress-responsive program limiting the proliferation of dama...
[会议论文] 作者:Sugeily Ramos Lorenzo,Tianhao Zhou,Heather Francis,Nan Wu,Julie Venter,Ying Wan,Shannon Glaser,Gianfranco Alpini, 来源:第九届广州国际干细胞与再生医学论坛暨第五届中国再生细胞生物学年会 年份:2016
  Background:Senescence of activated stellate cells limits hepatic fibrogenesis.Stem cell-derived extracellular vesicles(EVs)and their related microRNAs media...
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