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VSMC-derived XBP1u Deficiency Contributes to Abdominal Aortic Aneurysm via Regulating VSMC Phenotypi
[会议论文] 作者:Guizhen Zhao,Yi Fu,Qingbo Xu,Wei Kong,
来源:2016年国际生理学学术大会 年份:2016
Rationale: Vascular smooth muscle cell(VSMC)phenotypic switching proceeds the pathogenesis of abdominal aortic aneurysm(AAA).X-box binding protein 1(XBP1),a basic-region leucine zipper(bZIP)transcript...
XBP1 Deficiency in VSMC Contributes to Abdominal Aortic Aneurysm via Regulating VSMC Phenotypic Swit
[会议论文] 作者:Guizhen Zhao,Yi Fu,Qingbo Xu,Xian Wang,Wei Kong,
来源:中国生理学会基质生物学专业委员会成立大会暨第一次全国基质生物学学术会议 年份:2016
Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease,characterized by chronic vascular wall inflammation,extracellular matrix degrad...
[期刊论文] 作者:Jingang Zheng,Chenfeng Mao,Zhiqing Li,Zhixin Liu,Bing Yu,Tuoyi Li,Meili Wang,Chanjuan Xu,Yiwei Zhou,Guizhen Zhao,
来源:细胞研究(英文版) 年份:2021
Compelling evidence has revealed that biased activation of G protein-coupled receptor (GPCR) signaling,including angiotensin Ⅱ(Angll) receptor type 1 (AT1) signaling,plays pivotal roles in vascular homeostasis and injury,but whether a clin......
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