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[期刊论文] 作者:Bart A ELLENBROEK,Xue-xiang ZHANG,Guo-zhang JIN, 来源:中国药理学报(英文版) 年份:2006
Aim: (-)Stepholidine (SPD) is an active ingredient of the Chinese herb Stephania intermedia, which binds to the dopamine D1 and D2 like receptors. Biochemical,...
[期刊论文] 作者:Ke-chun YANGU,Guo-zhang JIN,Jie WU, 来源:中国药理学报(英文版) 年份:2009
Neuronal nicotinic acetylcholine receptors (nAChRs) are the superfamily of ligand-gated ion channels and widely expressed throughout the central and peripheral...
[会议论文] 作者:Die ZHANG,Guo-Zhang JIN,Xue-Chu ZHEN, 来源:中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份:2007
Clinical and experimental evidences have indicated that females appear to be more vulnerable than males to the reinforcing effects of psychostimulants.Gender differences have been repeated demonstrate...
[期刊论文] 作者:Yu FU,Zi-tao ZHU,Xing-zu ZHU,Guo-zhang JIN, 来源:中国药理学报(英文版) 年份:2004
AIM: To investigate the possibility whether THPB-18 (l-12-shloroscoulerine) possesses the D1 agonist-D2 antagonist action on meso-accumbens-mPFC DA system. METH...
[会议论文] 作者:Chang-Liang LIU,Guo-Zhang JIN,Xiao-Hua CAO,Xue-Chu ZHEN, 来源:中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份:2011
Oscillatory firing is an important process in neural system for presenting, integrating and synchronizing neuronal signals.Though most pyramidal neurons are able to oscillate at a broad band, only a f...
[期刊论文] 作者:Ming GAO,Chang-liang LIU,Shen YANG,Xue-chu ZHEN,Guo-zhang JIN, 来源:中国药理学报(英文版) 年份:2007
Aim: To investigate the effect ofl-stepholidine (SPD) on the frequency of spon-taneous excitatory postsynaptic currents (sEPSC) in the pyramidal cells between l...
[期刊论文] 作者:Wei-hua GU,Shen YANG,Wei-xing SHI,Guo-zhang JIN,Xue-chu ZHEN, 来源:中国药理学报(英文版) 年份:2007
Aim: To elucidate the role of scaffold protein postsynaptic density (PSD)-95 in the dopamine D1 receptor (D1R)-modulated NR 1a/NR2B receptor response.Methods: T...
[期刊论文] 作者:Wei-hua GU,Shen YANG,Wei-xing SHI,Xue-chu ZHEN,Guo-zhang JIN, 来源:中国药理学报(英文版) 年份:2007
Aim: To examine whether (-)-stepholidine (SPD) has a direct effect on the N-methyl-D-aspartic acid receptors (NMDAR) containing the NMDA receptor sub-units NR2A...
[期刊论文] 作者:Shang-lin ZHOU,Hong-yuan CHU,Guo-zhang JIN,Jian-min CUI,Xue-chu ZHEN, 来源:中国药理学报(英文版) 年份:2014
[会议论文] 作者:Xing FANG,Chang-Liang LIU,Qian-Qian Wu,Guo-Zhang JIN,Xue-Chu ZHEN, 来源:中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份:2011
The dopamine-containing neurons of the midbrain ventral tegmental area (VTA) play a critical role in the reinforcing effects of drugs of abuse.It has long been known that morphine can excite dopamine...
[期刊论文] 作者:Cheng XIAO,Ke-chun YANG,Chun-yi ZHOU,Guo-zhang JIN,Jie WU,Jiang-hong YE, 来源:中国药理学报(英文版) 年份:2009
Aim: Dopaminergic neurons in the substantia nigra pars compacta (SNc) play important roles in motor control and drug addiction. As the major afferent, GABAergic...
[会议论文] 作者:Pei-Hua SUN,Jing-Ru WANG,Wei-Hua GU,Jie ZHENG,Guo-Zhang JIN,Xue-Chu ZHEN, 来源:中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份:2007
PSD-95 is enriched in the postsynaptic density which has been shown to play an important role in the regulation of neurotransmitter receptor functions.The direct physical interaction between PSD-95 an...
[期刊论文] 作者:Zheng YANG,Yong-cong SHAO,Shi-jiang LI,Jian-lin QI,Mei-jie ZHANG,Wei HAO,Guo-zhang JIN, 来源:中国药理学报(英文版) 年份:2008
Aim: Drug addiction is a chronic brain disease with constant relapse requiring long-term treatment. New pharmacological strategies focus on the development of a...
[期刊论文] 作者:Xing FANG,Lin GUO,Jia JIA,Guo-zhang JIN,Bin ZHAO,Yong-yong ZHENG,Jian-qi LI, 来源:中国药理学报(英文版) 年份:2013
[期刊论文] 作者:Zhang Wei-guo,Liu Li-sheng,Zheng De-yu,Liu Guo-zhang,Jin Lu,Zhao Xiu-wen,Ren Bing, 来源:中华医学杂志英文版 年份:1992
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