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[期刊论文] 作者：Yi Shi,Hong-lei Ma,You-wen Zhuang,Xiao-xi Wang,Yi Jiang,H.Eric Xu,
来源：中国药理学报（英文版） 年份：2019
The polycomb repressive complex 2 (PRC2) catalyzes the methylation of histone H3 on lysine 27 (H3K27) to generate trimethyl-H3K27 (H3K27me3) marks,thereby leadi...
[期刊论文] 作者：Yi Shi,Ting Wang,X.Edward Zhou,Qiu-feng Liu,Yi Jiang,H.Eric Xu,
来源：中国药理学报（英文版） 年份：2019
Arthrobacter globiformis Uricase (AgUricase) is a homotetrameric uricase with the potential for therapeutic use in treating hyperuricemia-related diseases.To ac...
Structural basis for recognition of anti-migraine drug lasmiditan by the serotonin receptor 5-HT1F-G
[期刊论文] 作者：Sijie Huang,Peiyu Xu,Yangxia Tan,Chongzhao You,Yumu Zhang,Yi Jiang,H.Eric Xu,
来源：细胞研究（英文版） 年份：2021
Dear Editor,rnThe serotonin 5-HT1 receptor subtypes,including 5-HT1A,5-HT1B,5-HT1D,5-HT1E,and 5-HT1F,are G protein-coupled receptors(GPCRs)that respond to the endogenous neurotransmitter serotonin and couple preferentially to the Gi/o famil......
[期刊论文] 作者：Yue Zhao,Sanling Liu,Yingxin Zhou,Mengge Zhang,Haopeng Chen,H.Eric Xu,Demeng Sun,Lei Liu,Changlin Tian,
来源：细胞研究（英文版） 年份：2021
Dear Editor,rnNicotinic acetylcholine receptors (nAChRs) are a class of pentameric ligand-gated ion channels (pLGICs) widely expressed in nervous system.nAChRs function as neurotransmitter receptors that respond to endogenous acetylcholine ......
[期刊论文] 作者：Ping Liu,Yu-ling Yin,Ting Wang,Li Hou,Xiao-xi Wang,Man Wang,Guan-guan Zhao,Yi Shi,H.Eric Xu,Yi Jiang,
来源：中国药理学报（英文版） 年份：2019
5-HT4R,5-HT6R,and 5-HT7AR are three constitutively active Gs-coupled 5-HT receptors that have key roles in brain development,leaing,memory,cognition,and other p...
Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanoc
[期刊论文] 作者：Shanshan Ma,Yan Chen,Antao Dai,Wanchao Yin,Jia Guo,Dehua Yang,Fulai Zhou,Yi Jiang,Ming-Wei Wang,H.Eric Xu,
来源：细胞研究（英文版） 年份：2021
Melanocortins are peptide hormones critical for the regulation of stress response,energy homeostasis,inflammation,and skin pigmentation.Their functions are mediated by five G protein-coupled receptors (MC1R-MC5R),predominately through the s......
[期刊论文] 作者：Xiaomin Ma,Wanchao Yin,Tristan I.Croll,Qingtong Zhou,Xinheng He,Xiaokang Zhang,Dehua Yang,Peiyi Wang,H.Eric Xu,
来源：细胞研究（英文版） 年份：2021
Dear Editor,rnVasopressin type 2 receptor(V2R)belongs to the vasopressin(VP)/oxytocin(OT)receptor subfamily of G protein-coupled receptors(GPCRs),which comprises at least four closely related receptor subtypes:V1aR,V1bR,V2R,and OTR.1 These ......
[期刊论文] 作者：Xi-Ping Huang,Yongfeng Liu,Xi Cheng,Yi Jiang,Hualiang Jiang,Cheng Zhang,Wei Yi,Bryan L.Roth,Yan Zhang,H.Eric Xu,
来源：细胞研究（英文版） 年份：2021
Dear Editor,rnDopamine acts as an essential neurotransmitter whose signal-ing is conducted through five G protein-coupled receptors(GPCRs),dopamine D1 to D5 rec...
[期刊论文] 作者：Luan,Guanghui Tian,Haji A.Aisa,Yechun Xu,Gengfu Xiao,Jia Li,Hualiang Jiang,Shuyang Zhan,Leike Zhang,H.Eric Xu,
来源：细胞研究（英文版） 年份：2021
Dear Editor,rnSince the declaration of COVID-19 as a global pandemic on March 11,2020,this pandemic has been circulating for 17 months throughout the world,leading to more than 200 million infections and nearly 4A million deaths as of Augus......
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