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[期刊论文] 作者：Ahmed El-Shamy,Hak Hotta,,
来源：World Journal of Gastroenterology 年份：2014
Hepatitis C virus(HCV)is a major cause of liver disease worldwide.HCV is able to evade host defense mechanisms,including both innate and acquired immune respons...
[期刊论文] 作者：Takako Utsumi,Yoshihiko Yano,Hak Hotta,,
来源：World Journal of Medical Genetics 年份：2014
Although safe and effective vaccines against hepatitis B virus(HBV) have been available for three decades, HBV infection remains the leading cause of chronic he...
Hepatitis C virus NS3/4A with sequence variation at amino-terminus has different serine protease act
[期刊论文] 作者：Motoko Nagano-Fujii,Kikumi Kitayama,Hak Hotta,,
来源：Journal of Nanjing Medical University 年份：2009
Objective: To construct the point mutation plasmids expressing HCV NS3/4A with different secondary structures at the N-terminus, and to analyze their serine pro...
Prevalence and genotype distribution of hepatitis B virus among migrant workers in Lombok Island, In
[期刊论文] 作者：Navika Yamani,Eva Triani,Mochamad Amin,Juniastuti,Takako Utsumi,Soetjipto,Nasronudin,Yoshihiko Yano,Hak Hotta,
来源：亚太热带医药杂志（英文版） 年份：2020
Objective:To examine the potential risk of hepatitis B virus (HBV) spread in Indonesia by migrant workers,based on the molecular characteristics of HBV strains....
Antiviral activity of the dichloromethane extracts from Artocarpus heterophyllus leaves against hepa
[期刊论文] 作者：Tumewu,Aty Widyawaruyanti,Sri Puji Astuti Wahyuningsih,Tutik Sri Wahyuni,Maria Inge Lusida,Soetjipto,Hak Hotta,
来源：Asian Pacific Journal of Tropical Biomedicine 年份：2017
Objective: To determine anti-viral activities of three Artocarpus species: Artocarpus altilis, Artocarpus camansi, and Artocarpus heterophyllus(A. heterophyllus...
Mutational diversity of NSSA and NS3 during triple therapy (telaprevir, pegylated-interferon-alpha 2
[会议论文] 作者：WIDASARI,HANGGORO TRI RINONCE,MASAHIKO SUGANO,SATOSHI TANI,SEITETSU YOON,SUSUMU IMOTO,TAKESHI AZUMA,HAK HOTTA,
来源：2014中国传统医药国际健康服务高峰论坛 年份：2014
Background and aim: Telaprevir, a nonstructural (NS)3/4A protease inhibitor, is a direct-acting antiviral drug that inhibits viral replication.Triple therapy with telaprevir, pegylated interferon, and...
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