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[期刊论文] 作者：Wei Chen,Han-Ting Zhang,Shu-Cun Qin,
来源：神经科学通报（英文版） 年份：2021
Molecular hydrogen (H2) is a physiologically inert gas.However,during the last 10 years,increasing evidence has revealed its biological functions under patholog...
Phosphodiesterase-4(PDE4D)inhibitor rolipram and RNA interference-mediated knockdown of long-form PD
[会议论文] 作者：Cong Zhang,Chuang Wang,Han-Ting Zhang,Jiang-Ping Xu,
来源：中国药理学会抗炎免疫药理专业委员会成立30周年纪念大会暨2012年学术年会 年份：2012
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Phosphodiesterase-4(PDE4D)inhibitor rolipram and RNA interference-mediated knockdown of long-form PD
[会议论文] 作者：Cong Zhang,Chuang Wang,Han-Ting Zhang,Jiang-Ping Xu,
来源：中国药理学会抗炎免疫药理专业委员会成立30周年纪念大会暨2012年学术年会 年份：2012
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Rolipram,a selective phosphodiesterase-4 inhibitor,decreases ethanol seeking and consumption in alco
[会议论文] 作者：Rui-Ting WEN,Ming ZHANG,Wang-Jun QIN,Andrew J.Lawrence,Han-Ting ZHANG,Jian-Hui LIANG,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Alcohol dependence is a complex psychiatric disorder demanding development of novel pharmacotherapy.Since the cyclic AMP (cAMP) signaling cascade has been implicated in mediating the behavioral respon...
Rolipram inhibits the heroin-seeking behavior induced by heroin priming or heroin-associated conditi
[会议论文] 作者：Miao-Jun LAI,Hua-Qiang ZHU,Dan FU,Wei-Sheng CHENG,Han-Ting ZHANG,Wen-Hua ZHOU,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Objective Several lines of evidence have suggested a critical role for CREB activities, which activated by changes of cAMP in mediating the rewarding and reinforcement effects of many drugs of abuse.I...
[会议论文] 作者：Zhen-Zhen WANG,Ying HUANG,Marco Conti,Steven P.Wilson,James M.O'Donnell,Han-Ting ZHANG,Yun-Feng LI,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Objective Inhibition of phosphodiesterase-4 (PDE4) increases phosphorylation of the cAMP response element binding protein (pCREB) and hippocampal neurogenesis, and produces antidepressant-like and cog...
The phosphodiesterase-4 inhibitor rolipram reverses Aβ-induced cognitive impairment and neuroinflamm
[会议论文] 作者：Chuang WANG,Xue-Mei YANG,Ye-Ye ZHUO,Heng ZHOU,Huan-Bing LIN,Yu-Fang CHENG,Han-Ting ZHANG,Jiang-Ping XU,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Objective β-Amyloid (Aβ) peptides play an important role in cognition deficits, neuroinflammation, and apoptosis observed in Alzheimers disease (AD).Activation of cyclic AMP (cAMP) signaling enhances...
[会议论文] 作者：Han-Ting ZHANG,Steven P.WILSON,James M.O'DONNELL,Yun-Feng LI,Ying HUANG,Yu-Fang CHENG,Chuang WANG,Qiang,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Objective Phosphodiseterase (PDE) is a superfamily of enzymes that catalyzes the hydrolysis of intracellular cAMP and/or cGMP.Among the 11 PDE families (PDE1-11), PDE4 is the most important family in...
Leukotriene D4 induces cognitive impairment through enhancement of CysLT1Rmediated amyloid-β generat
[会议论文] 作者：HONG,Xiao-yun WANG,Yan LONG,Yong-qi Li,Guo-qing XIANG,Li-ying JIANG,Mei HU,Wei HU,Li-ping LIU,Han-ting ZHANG,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
...
Leukotriene D4 induces cognitive impairment through enhancement of CysLT1 R-mediated amyloid-β gener
[会议论文] 作者：Ting-Ting Zhang,Wei Hu,Hui Ji,Hao Hong,Xiao-Yun Wang,Yan Long,Yong-Qi Li,Guo-Qing Xiang,Li-Ying Jiang,Han-Ting Zhang,
来源：江苏省药理学会青年工作委员会成立大会暨药理学科青年科技创新学术研讨会 年份：2013
Aim: Amyloid plaques in the extracellular parenchyma mainly consist of amyloid-β peptides (Aβ), one of the pathological hallmarks in Alzheimers disease (AD).In the present study, we examined neuroinfl...
Leukotriene D4 induces cognitive impairment through enhancement of CysLT1Rmediated amyloid-β generat
[会议论文] 作者：Ting-ting ZHANG,Wei HU,Hui JI,Hao HONG,Xiao-yun WANG,Yan LONG,Yong-qi Li,Guo-qing XIANG,Li-ying JIANG,Han-ting ZHANG,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: Amyloid plaques in the extracellular parenchyma mainly consist of amyloid-β peptides (Aβ), one of the pathological hallmarks in Alzheimers disease (AD).In the present study, we examined neuroinfl...
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