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[期刊论文] 作者：Qing-Long Dong,Jian Ran,Han-Yu Yang,Li-Xia Liang,Bao-Yi Ouyang,
来源：海南医科大学学报（英文版） 年份：2019
Objective:To observe the incidence of residual neuromuscular blockade at the end of operation and during tracheal extubation, and analyze the risk factors causi...
Bile duct ligation causes opposite impacts on the expression and function of BCRP and P-gp in rat br
[期刊论文] 作者：Tong Wu,Yun Sheng,Yuan-yuan Qin,Wei-min Kong,Meng-meng Jin,Han-yu Yang,Xiao-ke Zheng,Chang Dai,Ming Liu,
来源：中国药理学报（英文版） 年份：2021
Breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp) are co-located at blood-brain barrier (BBB) cells,preventing their substrates from entering brain.Accumulating evidence demonstrates that liver failure impairs P-gp and BCRP ......
HACE1 negatively regulates neuroinflammation through ubiquitylating and degrading Rac1 in Parkinson&
[期刊论文] 作者：Cai-xia Zang,Lu Wang,Han-yu Yang,Jun-mei Shang,Hui Liu,Zi-hong Zhang,Cheng Ju,Fang-yu Yuan,Fang-yuan,
来源：中国药理学报（英文版） 年份：2022
Neuroinflammation plays an important role in neurodegenerative diseases,such as Parkinson\'s disease(PD)and Alzheimer\'s disease.HACE1(HECT domain and Ankyrin repeat Containing E3 ubiquitin-protein ligase 1)is a tumor suppressor.Recent evid......
,Bile duct ligation enhances AZT CNS toxicity partly by impairing the expression and function of BCR
[期刊论文] 作者：Yuan-yuan Qin,Ping Xu,Tong Wu,Chao-qun Qian,Yi-lin Fan,Dong-hao Gen,Liang Zhu,Wei-min Kong,Han-yu Yang,
来源：中国药理学报（英文版） 年份：2020
Breast cancer resistance protein (BCRP) is one of ATP-binding cassette (ABC) transporters in brain microvessel endothelial cells that transport their substrates...
,Characteristics of β-oxidative and reductive metabolism on the acyl side chain of cinnamic acid and
[期刊论文] 作者：Kai-jing Zhao,Yang Chen,Shi-jin Hong,Yi-ting Yang,Jiong Xu,Han-yu Yang,Liang Zhu,Ming Liu,Qiu-shi Xie,
来源：中国药理学报（英文版） 年份：2019
Cinnamic acid and its analogues (pyragrel and ozagrel) undergo chain-shortened (β-oxidative) and reductive metabolism on acyl side chain.In this study,we chara...
SKLB1206, a Novel Orally Available Multikinase Inhibitor Targeting EGFR Activating and T790M Mutants
[会议论文] 作者：Youli Pan,Yong Xu,Shan Feng,Shidong Luo,Renlin Zheng,Jiao Yang,Lijiao Wang,Lei Zhong,Han-Yu Yang,Bing-Lin,
来源：四川大学博士生学术论坛2015年年会 年份：2015
Anti-epidermal growth factor receptor(EGFR)treatment has been successfully applied in clinical cancer therapy.However,the clinical efficacy of first-generation reversible EGFR inhibitors,such as gefit...
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