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[会议论文] 作者：Ching-Chuan Kuo,Hsing-Pang Hsieh,Hsing-Jien Kung,
来源：2016第九届世界癌症大会 年份：2016
Cellular metabolism is substantially altered during tumor progression,and associated with poor prognosis and therapeutic resistance of human cancers.EGFR targeted agents currently under investigation...
[期刊论文] 作者：Vincent Blav,Mu-Chun Li,Sunita P.Ho,Mashall L.Stoller,Hsing-Pang Hsieh,Douglas R.Houston,
来源：药学学报（英文版） 年份：2020
Hepsin,a transmembrane serine protease abundant in renal endothelial cells,is a promising therapeutic target against several cancers,particularly prostate cance...
Design and Synthesis of Furano-Pyrimidine Analogs as Aurora Kinase Inhibitors:Optimization of Ligand
[会议论文] 作者：Hui-Yi Shiao,Selvaraj Mohane Coumar,Yi-Yu Ke,Wen-Hsing Lin,John Tsu-An Hsu,Yu-Sheng Chao,Hsing-Pang Hsieh,
来源：第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份：2012
We have recently reported furano-pyrimidine Aurora kinase A inhibitor 3(ligand efficiency,LE=0.25;liphophilic efficiency,LipE=1.75),with potent activity in vitro;however,3 was inactive in vivo.Based o...
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