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NRF2-GPX4/SOD2 axis imparts resistance to EGFR-tyrosine kinase inhibitors in non-small-cell lung can
[期刊论文] 作者：Chun-shuang Ma,Qian-ming Lv,Ke-ren Zhang,Ya-bin Tang,Yu-fei Zhang,Ying Shen,Hui-min Lei,Liang Zhu,
来源：中国药理学报（英文版） 年份：2021
Epidermal growth factor receptor-tyrosine kinase inhibitors(EGFR-TKIs)have achieved satisfactory clinical effects in the therapy of non-small cell lung cancer(N...
HKB99,an allosteric inhibitor of phosphoglycerate mutase 1,suppresses invasive pseudopodia formation
[期刊论文] 作者：Qian Liang,Wei-ming Gu,Ke Huang,Ming-yu Luo,Jing-hua Zou,Guang-lei Zhuang,Hui-min Lei,Hong-zhuan Chen,
来源：中国药理学报（英文版） 年份：2021
Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors(EGFR-TKIs),such as erlotinib,remains a major challenge in the targeted therap...
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