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[期刊论文] 作者:杨建民,Michael S Friedman,李峤,James J Mule,Alfred E Chang,Kevin T McDonagh,, 来源:中国肿瘤生物治疗杂志 年份:2006
目的:研究小鼠T淋巴细胞在转染嵌合性T细胞受体基因后的体外抗肿瘤作用。方法:应用重组DNA技术,将HER2特异性嵌合性T-细胞受体构建入逆转录病毒载体;转入包装细胞后,收集病毒...
[期刊论文] 作者:MICHAEL S FRIEDMAN,MARIANNE T HUBEN,JENNIFER FULLER,ALFRED E CHANG,JAMES J MULE,KEVIN T MCDONAGH,, 来源:Journal of Microbiology and Immunology 年份:2006
We have confirmed efficient anti-tumor activities of the peripheral lymphocytes transduced with a p185HER2-specific chimeric T-cell receptor gene both in murine...
[期刊论文] 作者:JIAN MIN YANG,MICHAEL S FRIEDMAN,MARIANNE T HUBEN,JENNIFER FULLER,QIAO LI,ALFRED E CHANG,JAMES J MULE, 来源:中华微生物学和免疫学杂志(英文版) 年份:2006
We have confirmed efficient anti-tumor activities of the peripheral lymphocytes transduced with a p185HER2-specific chimeric T-cell receptor gene both in murine...
[期刊论文] 作者:Michael S FRIEDMAN,Christopher M REYNOLDS,Marianne T HUBEN,Lee WILKE,Jennifer FULLER,李桥,Zelig ESHHAR,James J MULE, 来源:Journal of Microbiology and Immunology 年份:2004
We have developed and tested chimeric T-cell receptors (TCR) specific for p185HER2. In these experiments, retroviral vectors expressing the N29γ or N29ζ recep...
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