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Role of PDE4D splice variants in the mediation of antidepressant and cognition-enhancing actions and
[期刊论文] 作者：JIN Zeng-liang,WANG Zhen-zhen,,
来源：中国药理学与毒理学杂志 年份：2017
OBJECTIVE Phosphodiesterase 4(PDE4),specific for cyclicAMP(cAMP)-hydrolyzing,has four isoforms(PDE4A-D) with at least 25 splice variants. PDE4 inhibitors produc...
[会议论文] 作者：JIN Zeng-liang,LI Yun-feng,
来源：中国药理学会第十三次全国学术大会 年份：2015
Aim To characterize the SSRIs sensitivity in C57 and DBA mouse strain and identify the protein structural determinants that contribute to the SSRIs sensitivity.Methods Multiple behavioral assays were...
Mouse strain differences in selective serotonin reuptake inhibitors sensitivity correlates with sero
[期刊论文] 作者：JIN Zeng-liang,CHEN Xiao-fei,L,
来源：中国药理学与毒理学杂志 年份：2018
OBJECTIVE Selective serotonin reuptake inhibitors (SSRIs) bind 5-HT transporters, leading to the accumulation of 5-HT and amelioration of depression. Although d...
S1-2 The 5-HT6 Receptor-Related Mechanism for the Cognition-Enhancing Properties of Hypidone Hydroch
[期刊论文] 作者：JIN Zeng-liang,CHEN Xiao-fei,Z,
来源：神经药理学报 年份：2018
Hypidone hydrochloride(YL-0919),the 5-HT1A/6 agonists and 5-HT reuptake inhibitor,is a novel potent antidepressant with original chemical structure.Previous stu...
[会议论文] 作者：JIN Zeng-liang,CHENG Yu-fang,ZHOU Dan,XU Jiang-ping,
来源：第十五届中国神经精神药理学学术会议 年份：2012
OBJECTIVE Fructus Akebiae (FAE) is a tradi tional Chinese herbal that has been used for the treatment of de pressive disorders in China.To determine the content of heder agenin and identify the substa...
Role of PDE4D splice variants in the mediation of antidepressant and cognition-enhancing actions and
[期刊论文] 作者：JIN Zeng-liang,WANG Zhen-zhen,XU Yuan-yuan,YANG Wei-xing,LI Yun-feng,,
来源：中国药理学与毒理学杂志 年份：2017
OBJECTIVE Phosphodiesterase 4(PDE4),specific for cyclicAMP(cAMP)-hydrolyzing,has four isoforms(PDE4A-D) with at least 25 splice variants. PDE4 inhibitors produc...
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