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BM-IL12:G-quadruplex as targets in anticancer drug design:the design and evaluation of quindoline de
[会议论文] 作者:Tian-Miao Ou,Yu-Jing Lu,Jia-Heng Tan,Lian-Quan Gu,Zhi-Shu Huang,
来源:第13届亚洲化学大会(13th Asian Chemical Congress) 年份:2009
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BM-IL12:G-quadruplex as targets in anticancer drug design:the design and evaluation of quindoline de
[会议论文] 作者:Tian-Miao Ou,Yu-Jing Lu,Jia-Heng Tan,Lian-Quan Gu,Zhi-Shu Huang,
来源:第13届亚洲化学大会(13th Asian Chemical Congress) 年份:2009
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Specific Recognition of Quindoline Derivatives on Promoter G-Quadruplex and the Biological Relevance
[会议论文] 作者:Tian-miao Ou,Yue Wu,Jia-heng Tan,Lian-quan Gu,Zhi-shu Huang,
来源:第八届全国化学生物学学术会议 年份:2013
G-quadruplexes are unique secondary structure exist in various non-coding region of human genome and exhibit important biological roles in the regulation of gene replication, transcription, and transl...
[会议论文] 作者:Chan Shan,Jing Lin,Jin-Qiang Hou,Jia-Heng Tan,Tian-Miao Ou,Zhi-Shu Huang,
来源:2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份:2015
c-MYC is a classical G-quadruplex-relating gene that is considered as an effective target for anticancer therapy [1].The transcriptional factor NM23-H2 coul...
Small-Molecule-Induced Transcription Repression through Interfering with NM23-H2 Binding to G-quadru
[会议论文] 作者:Jing Lin,Chan Shan,Tian-Miao Ou,Jin-Qiang Hou,Shuo-bin Chen,Jia-Heng Tan,Lian-Quan Gu,Zhi-Shu Huang,
来源:全国药物化学学术会议暨第四届中英药物化学学术会议 年份:2013
NM23-H2 protein is identified as a transcriptional factor of the important oncogene c-myc,that can bind specifically to defined DNA sequences to promote gene transcription.However,due to its role in t...
[会议论文] 作者:Jin-Wu Yan,Wen-Jie Ye,Yan-ping Li,Jin-Qiang Hou,Jian-Hui Li,Jia-heng Tan,Tian-Miao Ou,Lian-Quan Gu,Zhi-Shu,
来源:第七届全国化学生物学学术会议 年份:2011
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Discovery of Novel Anti-tumour Agents for Specific Recognizing the G-quadruplex in 5-Untranslated Re
[会议论文] 作者:Shi-Ke Wang,Yue Wu,Xiao-Qin Wang,Guo-Tao Kuang,Qi Zhang,Giulia Biffi,Shu-Ling Lin,Hui-Yun Liu,Jia-Heng Tan,
来源:第九届全国核糖核酸(RNA)学术讨论会 年份:2016
Angiogenesis is important in tumorigenesis and tumor progress.Human vascular endothelial growth factor(hVEGF)is an angiogenic growth factor that plays a cru...
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