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Adaptor protein APPL1 couples synaptic NMDA receptor with neuronal pro-survival phosphatidylinositol
[会议论文] 作者：Jian-Hong Luo,
来源：Iternational Frontiers Symposium foe Neuron & Disease(国际神经与疾 年份：2012
It is well known that NMDARs can both induce neurotoxicity and promote neuronal survival under different circumstances.Recent studies show that such paradoxical responses are related to the receptor l...
[期刊论文] 作者：Xiao-Min Zhang,Jian-Hong Luo,,
来源：Neuroscience Bulletin 年份：2013
N-Methyl-D-aspartate receptors(NMDARs)play vital roles in the central nervous system,as they are primary mediators of Ca2+influx during synaptic activity.The su...
[期刊论文] 作者：Xing-Xing Xu,Jian-Hong Luo,
来源：神经科学通报（英文版） 年份：2018
Epilepsy is one of the most common neurological diseases.Of all cases,70％-80％ are considered to be due to genetic factors.In recent years,a large number of genes have been identified as being involved in epilepsy.Among them,N-methyl-D-asparta......
[期刊论文] 作者：Chan-ying ZHENG,Xiu-juan YANG,Zhan-yan FU,Jian-hong LUO,
来源：中国药理学报（英文版） 年份：2006
Aim: N-methyl-D-aspartate receptors (NMDAR) are heteromeric complexes primarily assembled from NR1 and NR2 subunits. In normal conditions, NR2 sub-units assembl...
[会议论文] 作者：Junyu Xu,Chuen Kam,Jian-hong Luo,Jun Xia,
来源：The 9th Asian Biophysics Association Symposium (ABA2015)(第九届 年份：2015
Formation of new synapses, or synaptogenesis, is critical for neuronal circuit formation in the brain.Neurexin-neuroligin interaction has been reported to induc...
[会议论文] 作者：Junyu Xu,Jun Xia,Chuen Kam,Jian-hong Luo,
来源：The 9th Asian Biophysics Association Symposium (ABA2015)(第九届 年份：2015
...
Sexual contact decreases contextual fear and prevents impairment of hippocampal long-term potentiati
[会议论文] 作者：Hua-yi BAI,Na LIU,Lin XU,Jian-hong LUO,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
Hippocampal long-term potentiation (LTP) is believed to be the mechanism underlying certain types of memory,which is exquisitely sensitive to stress.In the present study,we introduced a naïve fem...
,Visual recognition memory is related to basic expression level of NMDA receptor NR1/NR2B subtype in
[期刊论文] 作者：Shu-jun XU,Zhong CHEN,Li-jun ZHU,Hai-qing SHEN,Jian-hong LUO,
来源：中国药理学报（英文版） 年份：2005
Aim: To examine the basic expression levels of N-methyl-D-aspartate (NMDA) receptor NR1 and NR2B subunits in six brain regions of Sprague-Dawley (SD) rats with...
[期刊论文] 作者：Kai-yu ZHAN,Pei-lin YU,Chun-hui LIU,Jian-hong LUO,Wei YANG,
来源：中国药理学报（英文版） 年份：2016
...
Cysteine residues 87 and 320 in the amino terminal domain of NMDA receptor GluN2A govern its homodim
[期刊论文] 作者：Xiao-Min Zhang,Xin-You Lv,Yang Tang,Li-Jun Zhu,Jian-Hong Luo,,
来源：Neuroscience Bulletin 年份：2013
N-Methyl-D-aspartate receptors(NMDARs)play a central role in various physiological and pathological processes in the central nervous system.And they are commonl...
[会议论文] 作者：Shu-Jun XU,Di XIA,Gang CHEN,Jian-Hong LUO,Shu-Min DUAN,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
Niemann-Pick disease type C (NPC) is a progressive neurodegenerative disorder caused mainly by mutations of NPC 1 (95%).A biochemical hallmark of this disease is the intracellular accumulation of free...
,Influence of low dietary histamine on the seizure development of chemical kindling induced by penty
[期刊论文] 作者：Chun-lei JIN,Eiko SAKURAI,Yoshinobu KISO,Jian-hong LUO,Kazuhiko YANAI,Zhong CHEN,
来源：中国药理学报（英文版） 年份：2005
Aim: To determine the role of dietary low histamine on the seizure development of pentylenetetrazol (PTZ)-induced kindling in rats. Methods: After 14 d of feedi...
[期刊论文] 作者：Ying-Gang Yan,Jie Zhang,Shu-Jun Xu,Jian-Hong Luo,Shuang Qiu,Wei Wang,,
来源：Neuroscience Bulletin 年份：2014
N-methyl-D-aspartate receptors(NMDARs) containing different GluN2 subunits play distinct roles in synaptic plasticity.Such differences may not only be determine...
[会议论文] 作者：Ying GAO,Shuang-Shuang LIU,Shuang QIU,Wei CHENG,Jie ZHENG,Jian-Hong LUO,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
Acid-sensing ion channels (ASICs) are believed to be homo-or heteromeric complexes,which have been verified by classical methods such as co-immunoprecipitation or electrophysiological assays.However,t...
[期刊论文] 作者：Wei NING,Shu-jun XU,Huai CHIANG,Zheng-ping XU,Su-ya ZHOU,Wei YANG,Jian-hong LUO,
来源：中国药理学报（英文版） 年份：2007
Aim: To evaluate the effects of global system for mobile communications (GSM)1800 MHz microwaves on dendritic filopodia, dendritic arborization, and spine matur...
[会议论文] 作者：Yu-bin Wang,Jie-jie Wang,Shao-hua Wang,Shuang-Shuang Liu,Jing-yuan Cao,Xiao-ming Li,Shuang Qiu,Jian-hong Luo,
来源：International Conference for Physiological Sciences 2012(201 年份：2012
It is well known that NMDA receptors (NMDARs) can both induce neurotoxicity and promote neuronal survival under different circumstances.Recent studies show...
Neuroligins Differentially Mediate Subtype-Specific Synapse Formation in Pyramidal Neurons and Inter
[期刊论文] 作者：Qiang-Qiang Xia,Jing Xu,Tai-Lin Liao,Jie Yu,Lei Shi,Jun Xia,Jian-Hong Luo,Junyu Xu,
来源：神经科学通报（英文版） 年份：2019
Neuroligins (NLs) are postsynaptic cell-adhesion proteins that play important roles in synapse formation and the excitatory-inhibitory balance.They have been associated with autism in both human genetic and animal model studies,and affect s......
[会议论文] 作者：Ke-Xin LI,Jian-Hong LUO,Shu-Min DUAN,Xiao-Ming LI,Ying-Mei LU,Zheng-Hao XU,Jun-Ming ZHU,Jian-Ming ZHANG,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Neuregulin 1 (NRG1) is atrophic factor critical in neural development and synaptic plasticity.ErbB4, a key NRG1 receptor, is mainly expressed in glutamic acid decarboxylase (GAD)-positive neurons and...
[期刊论文] 作者：YAO,Gang WANG,Kun-fu OU-YANG,Chao-liang WEI,Xian-hua WANG,Shi-rong WANG,Wei YAO,Hong-ping HUANG,Jian-hong LUO,
来源：中国药理学报（英文版） 年份：2006
Aim: Ca2+ release from the endoplasmic reticulum (ER) is an integral component of neuronal Ca2+ signaling. The present study is to investigate properties of loc...
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