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Can remdesivir and its parent nucleoside GS-441524 be potential oral drugs?An in vitro and in vivo D
[期刊论文] 作者：Jiashu Xie,Zhengqiang Wang,
来源：药学学报（英文版） 年份：2021
Remdesivir (RDV) is the only US Food and Drug Administration (FDA)-approved drug for treating COVID-19.However,RDV can only be given by intravenous route,and there is a pressing medical need for oral antivirals.Significant evidence suggests......
[期刊论文] 作者：Kumar V.Vernekar,Rajkumar Lalji Sahani,Karen A.Kirby,Haijuan Du,Huanchun Zhang,Philip R.Tedbury,Jiashu Xie,
来源：药学学报（英文版） 年份：2021
Of all known small molecules targeting human immunodeficiency virus(HIV)capsid protein(CA),PF74 represents by far the best characterized chemotype,due to its ab...
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