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Extracellular Acidity in Tumors:A Phenomenon which Aids Tumor Growth,Can be Used to Yarget Drugs,and
[会议论文] 作者：Jonathan A.Coles,
来源：BIT‘s2nd Annual World Cancer Congess-2009 (2009第二届癌症大会) 年份：2009
The usefulness of targeting individual genetic mutations in cancer is limited by the huge variety of cancer genotypes.In contrast, the phenotypes of nearly all solid tumors include a high rate of lact...
More Evidence for the Importance of Extracellular Acidity;NHE1,A Proton Extruder Active in Invadopod
[会议论文] 作者：Jonathan A.Coles,Emmanuelle Grillon,Régine Farion,Katell Fable(t),Michel De Waard,Ming Tse,Mark Donowitz,
来源：BIT‘s2nd Annual World Cancer Congess-2009 (2009第二届癌症大会) 年份：2009
The extracellular spaces in nearly all tumors are acidic, a characteristic that may be useful for imaging aggressive tumors, and for targeting drugs (see Provent et al 2007, Cancer Res.67:7638).The Na...
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