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[会议论文] 作者：Jiaming Chen,Jiongyan Ding,Adrián Mari(n)o-Enríquez,Jonathan A.Fletcher,Wen-Bin Ou,
来源：中国生物化学与分子生物学会2019年全国学术会议 年份：2019
Gastrointestinal stromal tumor(GIST)is the most common malignant tumor of gastrointestinal tract.Mutated and activated Oncogene KIT and PDGFRA mutation and abnormal activation are the main factors for...
[会议论文] 作者：Shengmei Zhou,Jonathan A.Fletcher,Grant Eilers,Joseph M.Corson,Wen-Bin Ou,Li Liu,Hailong Li,Si Shi,Ziqing,
来源：第十一届全国酶学学术讨论会暨邹承鲁诞辰90周年纪念会 年份：2013
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[会议论文] 作者：Shengmei Zhou,Jonathan A.Fletcher,Wen-Bin Ou,Li Liu,Hailong Li,Grant Eilers,Si Shi,Ziqing Yan,Joseph,
来源：第十一届全国酶学学术讨论会暨邹承鲁诞辰90周年纪念会 年份：2013
Mesothelioma is a notoriously chemotherapy-resistant neoplasm, as is evident in the dismal overall survival for patients with this asbestos-associated disease.W...
[会议论文] 作者：Anastasios Kyriazoglou,Duolin Wu,Grant Eilers,George D.Demetri,Haibo Qiu,Adrian Marino-Enriquez,Jonathan A.Fletcher,
来源：中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 年份：2018
Purpose: Oncogenic KIT or PDGFRA tyrosine kinase mutations are compelling therapeutic targets in most gastrointestinal stromal tumors(GISTs),and the KIT/PDGFRA inhibitor,imatinib,is therefore standard...
Genome-wide functional screening identifies CDC37 as a crucial HSP90-cofactor for KIT oncogenic expr
[会议论文] 作者：Wen-Bin Ou,Ewa Sicinska,Jeffrey T.Czaplinski,Yuexiang Wang,Jonathan A.Fletcher,Anneliene H.Jonker,Mark,
来源：第十一届全国酶学学术讨论会暨邹承鲁诞辰90周年纪念会 年份：2013
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Genome-wide functional screening identifies CDC37 as a crucial HSP90-cofactor for KIT oncogenic expr
[会议论文] 作者：Wen-Bin Ou,Ewa Sicinska,Yuexiang Wang,Takahiro Taguchi,George D.Demetri,David E.Root,Jonathan A.Fletcher,
来源：第十一届全国酶学学术讨论会暨邹承鲁诞辰90周年纪念会 年份：2013
Most gastrointestinal stromal tumors (GISTs) contain KIT or PDGFRA kinase gain-of-function mutations, and therefore respond clinically to imatinib and other tyr...
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