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[期刊论文] 作者：Kai WANG,Hua-hao SHEN,Jun-chun CHEN,Zhong CHEN,
来源：中国药理学报(英文版) 年份：2005
Aim: To determine the effects of acetamide-45 on respiratory function, airway inflammation, and the activity of phosphodiesterase 4 (PDE4) in allergic rats.Meth...
Selective inhibition of purified human phosphodiesterase 4A expressed in yeast cell GL62 by ciclamil
[期刊论文] 作者：Jun-chun CHEN,Ji-qiang CHEN,Qiang-min Xie,Yi-liang ZHU,
来源：中国药理学报（英文版） 年份：2004
AIM: To improve the specific activity of human phosphodiesterase 4A (PDE4A) expressed in yeast cell GL62 and investigate the effects of selective phosphodiester...
Acetamide-45 inhibited hyperresponsiveness and airway inflammation in mice partly depending on phosp
[期刊论文] 作者：Kai WANG,Hua-hao SHEN,Hua-qiong HUANG,Jun-chun CHEN,Zhong CHEN,
来源：中国药理学报(英文版) 年份：2008
Aim:Asthma is characterized as a chronic inflammatory disorder of the airways.Phosphodiesterases (PDE),which hydrolyze cAMP,are considered to play important rol...
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