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Strategies to promote the maturation of ALS-associated SOD1 mutants:small molecules return to the fo
[期刊论文] 作者:Luke McAlary,Justin J.Yerbury,
来源:中国神经再生研究:英文版 年份:2019
(Cu)^IIATSM(CuATSM)promotes the proper folding of familial amyotrophic lateral sclerosis(fALS)-associated copper,zinc superoxide dismutase(SOD1):ALS is a progre...
[期刊论文] 作者:Ronald Sluyter,Rachael Bartlett,Diane Ly,Justin J.Yerbury,,
来源:Neural Regeneration Research 年份:2017
Amyotrophic lateral sclerosis(ALS)is a rapidly progressive disorder characterized by the degeneration and subsequent loss of upper and lower motor neurons,resul...
Ubiquitin homeostasis disruption, a common cause of proteostasis collapse in amyotrophic lateralscle
[期刊论文] 作者:Christen G.Chisholm,Jeremy S.Lum,Natalie E.Farrawell,Justin J.Yerbury,
来源:中国神经再生研究(英文版) 年份:2022
Amyotrophic lateral sclerosis (ALS) is associated with proteostasis collapse: ALS is an unrelenting neurodegenerative disease that is characterized by the loss of motor neurons in the brain and spinal cord, resulting in the progressive atro......
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