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[期刊论文] 作者:杨建民,Kevin T MCDONAGH,,
来源:中国肿瘤生物治疗杂志 年份:2007
异基因造血干细胞移植后供体淋巴细胞输注治疗恶性血液病的成功进一步增强了人们应用细胞免疫治疗恶性肿瘤的信心。但从每一位患者体内克隆出肿瘤细胞特异性的CTL,并在体外扩...
[期刊论文] 作者:杨建民,Michael S Friedman,李峤,James J Mule,Alfred E Chang,Kevin T McDonagh,,
来源:中国肿瘤生物治疗杂志 年份:2006
目的:研究小鼠T淋巴细胞在转染嵌合性T细胞受体基因后的体外抗肿瘤作用。方法:应用重组DNA技术,将HER2特异性嵌合性T-细胞受体构建入逆转录病毒载体;转入包装细胞后,收集病毒...
In vivo anti-tumor activity of murine hematopoietic stem cells expressing a p185HER2-specific chimer
[期刊论文] 作者:MICHAEL S FRIEDMAN,MARIANNE T HUBEN,JENNIFER FULLER,ALFRED E CHANG,JAMES J MULE,KEVIN T MCDONAGH,,
来源:Journal of Microbiology and Immunology 年份:2006
We have confirmed efficient anti-tumor activities of the peripheral lymphocytes transduced with a p185HER2-specific chimeric T-cell receptor gene both in murine...
,In vivo anti-tumor activity of marine hematopoietic stem cells expressing a p185HER2-specific chime
[期刊论文] 作者:YANG,MICHAEL S FRIEDMAN,MARIANNE T HUBEN,JENNIFER FULLER,QIAO LI,ALFRED E CHANG,JAMES J MULE,KEVIN T MCDONAGH,
来源:中华微生物学和免疫学杂志(英文版) 年份:2006
We have confirmed efficient anti-tumor activities of the peripheral lymphocytes transduced with a p185HER2-specific chimeric T-cell receptor gene both in murine...
Tumor Antigen Specific Activation of Primary Human T-Cells Expressing a Virally Encoded Chimeric T-C
[期刊论文] 作者:Christopher M REYNOLDS,Marianne T HUBEN,Lee WILKE,Jennifer FULLER,李桥,Zelig ESHHAR,James J MULE,Kevin T MCDONAGH,
来源:Journal of Microbiology and Immunology 年份:2004
We have developed and tested chimeric T-cell receptors (TCR) specific for p185HER2. In these experiments, retroviral vectors expressing the N29γ or N29ζ recep...
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