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Selective Preparation of Metastable Polymorphs of Oral Hypoglycemic Agents Using Cyclodextrin Comple
[会议论文] 作者:Fumitoshi Hirayama,Daisuke Iohara,Kaneto Uekama,
来源:首届亚洲药物制剂科学研讨会(1st Asian Pharmaceutical Science and Technolog 年份:2007
Purpose: The study was conducted to investigate effects of cyclodextrins (CyDs) on crystallizations and polymorphic transitions of oral hypoglycemic agents, tolbutamide and chlorpropamide, in aqueous...
[会议论文] 作者:Taishi Higashi,Fumitoshi Hirayama,Hidetoshi Arima,Kaneto Uekama,
来源:首届亚洲药物制剂科学研讨会(1st Asian Pharmaceutical Science and Technolog 年份:2007
The monosubstituted insulin with poly(ethyleneglycol) (PEG, MW about 2200) formed polypseudorotaxanes with αand γ-cyclodextrins (CyDs), by inserting one PEG chain of the pegylated insulin in the α-CyD...
[会议论文] 作者:Daisuke Iohara,Fumitoshi Hirayama,Takako Ishiguro,Hidetoshi Arima,Kaneto Uekama,
来源:首届亚洲药物制剂科学研讨会(1st Asian Pharmaceutical Science and Technolog 年份:2007
Purpose: To investigate the effects of cyclodextrin (CyD) derivatives on crystallization and solution-mediated polymorphic transition of indomethacin in aqueous solution.Methods: Indomethacin crystals...
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