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Incorporating historical data in Bayesian phase Ⅰ trial design:Evaluating the similarity in dose-tox
[会议论文] 作者：Kentaro Takeda,Satoshi Morita,
来源：上海交通大学 年份：2016
In oncology area,following a phase Ⅰ dose-finding trial completed in a certain population of patients,further phase Ⅰ trials are often conducted to determine the maximum tolerated dose(MTD)for differe...
[会议论文] 作者：Masataka Taguri,Kentaro Takeda,Satoshi Morita,
来源：上海交通大学 年份：2016
One of the main purposes of a phase dose-finding trial in oncology is to identify a tolerable dose with an indication of therapeutic benefit to administer to subjects in subsequent phase Ⅱ and Ⅲ trial...
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