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OP16,a novel derivative of oridonin,potentiates the antitumor effect of rapamycin by inhibiting rapa
[会议论文] 作者:Guiqin Hou,Kezheng Peng,Yu Ke,Qi Zhao,Yiru Bai,Fei Tian,Yingying Shi,Zhaoming Lu,Hongmin Liu,
来源:2016医学科学前沿暨第四届个体化治疗与抗肿瘤药物研究新趋向研讨会 年份:2016
Backgrounds and Purpose: Rapamycin,an mTORC1 allosteric inhibitor with broad antitumor effects,could induce the activation of numerous negative feedback loops such as PI3K/Akt/mTOR signaling pathway,w...
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