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AMP-activated protein kinase-dependent autophagy mediated the protective effect of sonic hedgehog pa
[会议论文] 作者：Luo jian-dong,Xiao Qing,
来源：广东省药理学会第七届2015学术交流大会 年份：2015
Aims: Previous study from our lab reported that sonic hedgehog (Shh) pathway plays a protective role in myocardial infarction (MI) through against the damage of cardiomyocytes,but the underlying mecha...
Leptin Attenuates Contractile Function in Adult Rat Cardiomyocytes Involved Oxidative Stress and Aut
[会议论文] 作者：ZHANG Gen-shui,LUO Liu-jin,LUO Jian-dong,
来源：中国药理学会第十三次全国学术大会 年份：2015
Aim Leptin, a 16 ku hormone from the ob gene, has been identified as an important protein involved obesity.As a chronic metabolic disorder, Obesity is associated with a high risk of developing cardiov...
[会议论文] 作者：HOU Ning,MAI Yun-pei,LI Su-juan,LUO Jian-dong,
来源：中国药理学会第十三次全国学术大会 年份：2015
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Maternal obesity causes a sex-dependent increase in AT2 R expression and cardiac dysfunction in adul
[会议论文] 作者：XUE Qin,CHEN Pin-xian,LI Xiong-xiong,ZHANG Gui-ping,LUO Jian-dong,
来源：中国药理学会第十三次全国学术大会 年份：2015
Aim Maternal obesity is associated with cardiovascular disease later in life.Here we report that maternal obesity causes programming of increased cardiac AT2 receptor (AT2R) expression, resulting in h...
Proteasome inhibition ameliorates cardiomyocyte hypertrophy through GSK-3α/β pathway in primary neon
[会议论文] 作者：LIU Ying-hua,ZHANG Gui-ping,LUO Jian-dong,LI Su-juan,WEI Wei,CHEN Kui-xiang,WU Jian-hui,HOU Ning,WANG,
来源：中国药理学会第十三次全国学术大会 年份：2015
Aim Previous studies showed that the inhibition of proteasome activity could significantly improve cardiac hypertrophy, but its mechanism is not clear.Increased glycogen synthase kinase3 (GSK3) activi...
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