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A High Throughput Technique for Identification of Ideal Folding Conditions for Regeneration of Thera
[会议论文] 作者:Mahesh Narayan,
来源:第四届生命之春论坛 年份:2008
The endoplasmic reticulum resident oxidoreductase, protein disulfide isomerase (PDI), catalyzes the acquisition of native disulfide bonds in multi-disulfide-bond-containing proteins.The rate-determini...
Targeting Nitrosative Stress Effects on an ER-resident Oxidoreductase through Small-molecule Ethnoph
[会议论文] 作者:Mahesh Narayan,
来源:2008中国深圳蛋白质和多肽科学大会 年份:2008
Misfolded proteins,and the associated endoplasmic reticulum (ER) stress,are emerging as hallmarks of age-and neurodegeneration-related disorders such as Huntingtons disease (HD),Alzheimers disease (AD...
A High-throughput Technique for Identification of Ideal Folding Conditions for Regeneration of Thera
[会议论文] 作者:Mahesh Narayan,Ervin Welker,Huili Zhai,Xuemei Han,Guoqiang Xu,Fred W.McLafferty,Harold A.Scheraga,
来源:2008中国深圳蛋白质和多肽科学大会 年份:2008
High-throughput in vitro refolding of disulfide-bond-containing proteins is particularly challenging because their aggregation competes with their refolding...
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