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Simultaneous evaluation of the effects of test articles on the respiratory, cardiovascular and centr
[会议论文] 作者：Chengjun Ma,Kazuaki Sasaki,Yasuo Nakamura,Masakazu Imaizumi,Seiichi Katayama,
来源：中国药理学会安全药理学专业委员会成立大会暨第四届安全药理学国际学术研讨会 年份：2015
In guideline for safety pharmacology core battery, the unanesthetized and unrestrained animals are preferable to use, and three Rs (replacement, reduction and refinement) are required for more ethical...
Species differences of effects of morphine on respiratory function in Sprague-Dawley rats, beagle do
[会议论文] 作者：Cheng-jun Ma,Kazuaki Sasaki,Yasuo Nakamura,Masakazu Imaizumi,Seiichi Katayama,Katsuhide Nishi,
来源：2015年(第五届)药物毒理学年会 年份：2015
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Species differences of effects of morphine on respiratory function in Sprague-Dawley rats, beagle do
[会议论文] 作者：Cheng-jun Ma,Kazuaki Sasaki,Yasuo Nakamura,Masakazu Imaizumi,Seiichi Katayama,Katsuhide Nishi,
来源：2015年(第五届)药物毒理学年会 年份：2015
[Purpose] Rats are frequently used for respiratory safety in most investigational new drug programs, but large animals are perhaps more appropriated due to their closer biologic similarities to humans...
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