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[会议论文] 作者：Meiyu Geng,
来源：The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份：2015
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[期刊论文] 作者：Min Huang,Meiyu Geng,,
来源：Science China(Life Sciences) 年份：2017
Perturbations of the epigenomic landscape,as defined by genome-wide localization of histone post-translational modifications,DNA methylations and chromatin...
Simm530, a novel highly selective c-Met inhibitor,blocks c-Met-dependent signaling and neoplastic ac
[会议论文] 作者：Jing Ai,Meiyu Geng,
来源：3rd International Conference on Fibroblast Growth Factors (F 年份：2012
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Simm530, a novel highly selective c-Met inhibitor,blocks c-Met-dependent signaling and neoplastic ac
[会议论文] 作者：Jing Ai,Meiyu Geng,
来源：3rd International Conference on Fibroblast Growth Factors (F 年份：2012
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[期刊论文] 作者：Zuoquan Xie,Hong Liu,Meiyu Geng,,
来源：Science China(Life Sciences) 年份：2017
Sphingosine-1-phosphate(S1P) is a potent pleotropic bioactive lipid mediator involved in immune cell trafficking, cell survival,cell proliferation, cell migrati...
[期刊论文] 作者：Feifei Liu,Xiaotong Yang,Meiyu Geng,Min Huang,
来源：药学学报（英文版） 年份：2018
The mitogen-activated protein kinases (MAPK) pathway, often known as the RAS-RAFMEK-ERK signal cascade, functions to transmit upstream signals to its downstream...
[期刊论文] 作者：Ruilin Song,Guowei Sang,Meiyu Geng,Hualiang Jiang,
来源：国家科学评论（英文版） 年份：2019
On 9 August 2015,the State Council of the Peoples Republic of China issuedThe Opinions on Reforming Review and Approval Process for Drugs and Medical Devices (G...
[会议论文] 作者：Hong Cui,Wei Zhang,Yingxia Li,Meiyu Geng,
来源：2015年全国药物化学学术会议暨第五届中英药物化学学术会议 年份：2015
c-Met is one of receptor tyrosine kinase,expressed in normal and tumor cells are present [1].In human cancers,c-Met signaling pathway in the one of the most frequent disorders of the pathway,c-Met sig...
[会议论文] 作者：Zhiqing Liu,Jing Ai,Zilan Song,Xia Peng,Yi Wang,Meiyu Geng,Ao Zhang,
来源：全国药物化学学术会议暨第四届中英药物化学学术会议 年份：2013
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Design, Synthesis and Biological Evaluation of 6-(2,6-dichloro-3,5-dimethoxyphenyl)-4-Substituted-1H
[会议论文] 作者：Zhen Zhang,Dongmei Zhao,Yang Dai,Maosheng Cheng,Meiyu Geng,Yuchi Ma,Jing Ai,Bing Xiong,Jingkang Shen,
来源：2016年长三角药物化学研讨会 年份：2016
Tyrosine kinase fibroblast growth factor receptor (FGFR),which is aberrant in various cancer types,is a promising target for cancer therapy[1-4].Thus,discovery of potent and selective FGFR inhibitors...
[期刊论文] 作者：Danqi Chen,Aijun Shen,Guanghua Fang,Hongchun Liu,Minmin Zhang,Shuai Tang,Bing Xiong,Lanping Ma,Meiyu Geng,
来源：Acta Pharmaceutica Sinica B 年份：2016
Histone acetylation is a critical process in the regulation of chromatin structure and gene expression.Histone deacetylases(HDACs)remove the acetyl group,leadin...
Chromopeptide A, a highly cytotoxic depsipeptide from the marine sediment-derived bacterium Chromoba
[期刊论文] 作者：Zhenfang Zhou,Xin Wang,Hui Zhang,Jingya Sun,Linghui Zheng,Hongchun Liu,Jidong Wang,Aijun Shen,Meiyu Geng,
来源：Acta Pharmaceutica Sinica B 年份：2015
A bicyclic depsipeptide, chromopeptide A(1), was isolated from a deep-sea-derived bacterium Chromobacterium sp. HS-13-94. Its structure was determined by extens...
[会议论文] 作者：Guihua Huang,Yumei Cheng,Deheng Wang,Chunpu Li,Ming Du,Jianhua Sun,Qiuping Qin,Hong Liu,Meiyu Geng,Likun,
来源：第二届(2016年)中国安全药理学学术年会暨第五届安全药理学国际学术研讨会 年份：2016
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Pharmacokinetics,distribution,and excretion of sodium oligomannate,a recently approved anti-Alzheime
[期刊论文] 作者：Jiaojiao Lu,Qiongqun Pan,Jieqiang Zhou,Yan Weng,Kaili Chen,Lv Shi,Guanxiu Zhu,Chunlin Chen,Liang Li,Meiyu Geng,
来源：药物分析学报（英文版） 年份：2022
The National Medical Products Administration has authorized sodium oligomannate for treating mild-to-moderate Alzheimer\'s disease.In this study,an LC-MS/MS method was developed and validated to quantitate sodium oligomannate in different b......
Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies no
[会议论文] 作者：,Zhongjie Liang,Limin Chen,Liyi Zhang,Hao Zhang,Hong Liu,Hualiang Jiang,Bairong Shen,Ming Huang,Meiyu Geng,
来源：第八届国际分子模拟与信息技术应用学术会议 年份：2016
The connection between inflammation and tumourigenesis has been well established.However,the detailed molecular mechanism underlying inflammation-associated tumourigenesis remains unknown because this...
[期刊论文] 作者：Peng Wei,Bo Liu,Ruifeng Wang,Yinglei Gao,Lanlan Li,Yuchi Ma,Zhiwei Qian,Yuelei Chen,Maosheng Cheng,Meiyu Geng,
来源：药学学报（英文版） 年份：2019
Genomic alterations are commonly found in the signaling pathways of fibroblast growth factor receptors (FGFRs).Although there is no selective FGFR inhibitors in...
Design,synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FG
[期刊论文] 作者：Yulan Wang,Chunpu Li,Xia Peng,Jihui Zhao,Bao Wang,Yang Dai,Dan Feng,Tianbiao Yang,Hualiang Jiang,Meiyu Geng,
来源：药学学报（英文版） 年份：2021
Fibroblast growth factor receptors(FGFRs)have emerged as promising targets for anticancer therapy.In this study,we synthesized and evaluated the biological acti...
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