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Multiple glial-neuronal dialogues in morphine tolerance:role of P2X7 receptor downstream cascades in
[会议论文] 作者：Meng-Ling CHEN,Hong CAO,Long-Zhen CHENG,Yu-Xia CHU,Yu-Qiu ZHANG,Zhi-Qi ZHAO,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Objective Morphine is a potent analgesic.However, its clinical application is restricted due to morphine tolerance.The underlying mechanism is not fully understood.Glia are thought to be involved in m...
Role of P2X7 receptor-mediated IL-18/IL-18R signaling in morphine tolerance: multiple glial-neuronal
[会议论文] 作者：Hong Cao,Meng-Ling Chen,Yu-Xia Chu,Long-Zhen Cheng,Yu-Qiu Zhang,Zhi-Qi Zhao,
来源：International Conference for Physiological Sciences 2012(201 年份：2012
The glial function in morphine tolerance has been explored, but its mechanisms remain unclear.Our previous study has showed that microglia-expressed P2X7 receptors (P2X7R) contribute to the induction...
Spinal mechanisms of bone cancer pain and tolerance to morphine analgesia:cross-talk between neurons
[会议论文] 作者：Meng-Ling CHEN,Yan YANG,Dong ZHOU,Ting-Ting LI,Hong CAO,Yu-Qiu ZHANG,Zhi-Qi ZHAO,
来源：中国神经科学学会第九届全国学术会议暨第五届会员代表大会 年份：2011
Cancer pain is one of the most severe type of chronic pain.The most common cancer pain is caused by tumors that metastasize from distant sites such as breast, prostate, and lung to the bone.Morphine i...
[会议论文] 作者：Shang-Feng GAO,Chun CHENC,Shu-Qiong NIU,Jing QIN,Xin LI,Shu-Xian SHI,Meng-Ling CHEN,Ai-Guo SHEN,
来源：中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the 年份：2007
Postsynaptic density-95 (PSD-95) is a scaffolding protein at excitatory synapses linking N-methyl-D-aspartate receptor (NMDAR) with neuronal nitric oxide synthase (nNOS),which contributes many physiol...
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