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,Discovery, synthesis, biological evaluation and structure-based optimization of novel piperidine de
[期刊论文] 作者：Jian SHEN,Xi-cheng YANG,Ming-cheng YU,Li XIAO,Xun-jie ZHANG,Hui-jiao SUN,Hao CHEN,
来源：中国药理学报（英文版） 年份：2017
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Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (R
[期刊论文] 作者：Ming-cheng Yu,Feng Yang,Xiao-yu Ding,Nan-nan Sun,Zheng-yuan Jiang,Ya-fei Huang,Yu-rong Yan,Chen Zhu,Qiong,
来源：中国药理学报（英文版） 年份：2021
A series of 6-substituted carbazole-based retinoic acid-related orphan receptor gamma-t (RORγt) modulators were discovered through 6-position modification guided by insights from the crystallographic profiles of the “short” inverse agoni......
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