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[期刊论文] 作者：Xiaojuan He,Moshi Song,Jing Qu,Yansu Guo,Heqi Cao,Ruijuan Sun,Guang-Hui Liu,Yong Shen,Major Program Expert,
来源：蛋白质与细胞 年份：2019
Based on a national survey conducted by the National Bureau of Statistics, Chinas elderly population (aged 60 and above) had reached 249 million by the end of 2...
[期刊论文] 作者：Shijia Bi,Zunpeng Liu,Zeming Wu,Zehua Wang,Xiaoqian Liu,Si Wang,Jie Ren,Yan Yao,Weiqi Zhang,Moshi Song,
来源：蛋白质与细胞 年份：2020
SIRT7,a sirtuin family member implicated in aging and disease,is a regulator of metabolism and stress responses.It remains elusive how human somatic stem cell p...
,CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-κB/RelA in maintaining the homeost
[期刊论文] 作者：Zunpeng Liu,Xiaoqian Zhang,Jingyi Li,Liang Sun,Zhenyu Ju,Jian Li,Piu Chan,Guang-Hui Liu,Weiqi Zhang,Moshi Song,
来源：蛋白质与细胞 年份：2018
Vascular cell functionality is critical to blood vessel homeostasis.Constitutive NF-κB activation in vascular cells results in chronic vascular inflammation,le...
[期刊论文] 作者：Lingling Geng,Zunpeng Liu,Si Wang,Shuhui Sun,Shuai Ma,Xiaoqian Liu,Piu Chan,Liang Sun,Moshi Song,Weiqi,
来源：蛋白质与细胞 年份：2019
Dear Editor,Aging is the leading risk factor for many chronic diseases,accounting for almost 60％ of all deaths worldwide.How to achieve healthy aging,alleviate a...
[期刊论文] 作者：Zeming WU,Xiaoqian Liu,Sheng Zhang,Qianzhao Ji,Xiaoyu Jiang,Zunpeng Liu,Si Wang,Jing Qu,Weiqi Zhang,Moshi Song,
来源：蛋白质与细胞 年份：2020
Dear Editor,rnAs the most prevalent DNA methylation modification in prokaryotes, DNA N6-methyladenosine (6mA)in eukaryotic genomes has recently been observed in...
[期刊论文] 作者：Fang Cheng,Si Wang,Moshi Song,Zunpeng Liu,Ping Liu,Lei Wang,Yanjiang Wang,Qian Zhao,Kaowen Yan,Piu Chan,
来源：蛋白质与细胞 年份：2019
Dear Editor,Safeguarding cellular redox homeostasis is crucial for maintaining organism health and preventing diseases.Oxidative stress,often characterized by d...
[期刊论文] 作者：Weiqi Zhang,Wei Li,Zeming Wu,Wei Wang,Ruotong Ren,Yao Su,Peichang Wang,Liang Sun,Zhenyu Ju,Piu Chan,Moshi Song,
来源：蛋白质与细胞 年份：2019
Aging increases the risk of various diseases.The main goal of aging research is to find therapies that attenuate aging and alleviate aging-related diseases.In t...
[期刊论文] 作者：Chen Ling,Zunpeng Liu,Moshi Song,Weiqi Zhang,Si Wang,Xiaoqian Liu,Shuai Ma,Shuhui Sun,Lina Fu,Qun Chu,
来源：蛋白质与细胞 年份：2019
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencaphalopathy (CADASIL) is a rare hereditary cerabrovascular disease caused by a NO...
[期刊论文] 作者：Zeming Wu,Weiqi Zhang,Moshi Song,Wei Wang,Gang Wei,Wei Li,Jinghui Lei,Yu Huang,Yanmei Sang,Piu Chan,Chang,
来源：蛋白质与细胞 年份：2018
Hutchinson-Gilford progeria syndrome (HGPS) and Wemer syndrome (WS) are two of the best characterized human progeroid syndromes.HGPS is caused by a point mutati...
[期刊论文] 作者：Jingyi Li,Yuxuan Zheng,Pengze Yan,Moshi Song,Si Wang,Liang Sun,Zunpeng Liu,Shuai Ma,Juan Carlos Izpisua,
来源：国家科学评论（英文版） 年份：2021
Aging-related degeneration of pancreatic islet cells contributes to impaired glucose tolerance and diabetes.Endocrine cells age heterogeneously,complicating the...
FOXO3-engineered human mesenchymal progenitor cells efficiently promote cardiac repair after myocard
[期刊论文] 作者：Concepcion Rodriguez Esteban,Yan Yao,Juan Carlos Izpisua Belmonte,Piu Chan,Guang-Hui Liu,Weiqi Zhang,Moshi Song,
来源：蛋白质与细胞 年份：2021
Dear Editor,rnMyocardial infarction(MI)is the irreversible cardiomyocyte death resulting from prolonged oxygen deprivation due to obstructed blood supply(ischem...
,Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis
[期刊论文] 作者：Xiaojuan He,Shuhui Sun,Shuai Ma,Ng Shyh-Chang,Feng Liu,Qiang Wang,Xiaoqun Wang,Lin Liu,Weiqi Zhang,Moshi Song,
来源：蛋白质与细胞 年份：2019
RAP1 is a well-known telomere-binding protein,but its functions in human stem cells have remained unclear.Here we generated RAP1-deficient human embryonic stem...
Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration
[期刊论文] 作者：Chuqian Liang,Zunpeng Liu,Moshi Song,Wei Li,Zeming Wu,Zehua Wang,Qiaoran Wang,Si Wang,Kaowen Yan,Liang,
来源：细胞研究（英文版） 年份：2021
Accumulating evidence indicates an association between the circadian clock and the aging process.However,it remains elusive whether the deregulation of circadia...
[期刊论文] 作者：,Lihui Xie,He Li,Wen Wen,Si Wang,Shuai Ma,Zhaohao Huang,Jinguo Ye,Wen Shi,Yanxia Ye,Zunpeng Liu,Moshi Song,
来源：蛋白质与细胞 年份：2020
Age-associated changes in immune cells have been linked to an increased risk for infection.However,a global and detailed characterization of the changes that hu...
[期刊论文] 作者：Si Wang,Yuxuan Zheng,Qingqing Li,Xiaojuan He,Ruotong Ren,Weiqi Zhang,Moshi Song,Huifang Hu,Feifei Liu,
来源：蛋白质与细胞 年份：2021
Dear Editor,rnThe retina is a light-sensitive highly-organized tissue,which is vulnerable to aging and age-related retinal diseases.Specifically,progressive retinal degeneration leads to visual function deterioration and vision impairment i......
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