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Design and synthesis of novel dual inhibitors of NF-KB and Akt activation against lung adenocarcinom
[会议论文] 作者:Manu Sharma,Navin Tailor,Suthar Kumar,
来源:22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会) 年份:2013
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Design and synthesis of novel dual inhibitors of NF-KB and Akt activation against lung adenocarcinom
[会议论文] 作者:Manu Sharma,Navin Tailor,Suthar Kumar,
来源:22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会) 年份:2013
Objective: The C-2 arylidene analogs ofpentacyclic triterpenoid Lantadene A (1) and B (2) were synthesized as dual inhibitors of NF-iB and Akt.The compounds were further evaluated for in vivo anticanc...
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