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[期刊论文] 作者:Niki Karachaliou,Maria Gonzale, 来源:癌症生物学与医学:英文版 年份:2015
Survival rates for metastatic lung cancer, including non-small cell lung cancer(NSCLC) and small cell lung cancer(SCLC), are poor with 5-year survivals of less...
[期刊论文] 作者:Niki Karachaliou,Rafael Rosell,, 来源:Cancer Biology & Medicine 年份:2014
Lung cancer is the most frequently diagnosed cancer and a leading cause of cancer mortality worldwide, with adenocarcinoma being the most common histological su...
[期刊论文] 作者:Rafael Rosell,Niki Karachaliou, 来源:临床与病理杂志 年份:2015
人们普遍认为有必要对非小细胞肺癌进行分子层面的分析.例如,基于EGFR突变状态的治疗已经得到了很好的研究结果.尽管口服EGFR酪氨酸激酶抑制剂(TKIs)在初始治疗中能够取得较...
[期刊论文] 作者:Niki Karachaliou,Rafael Rosell, 来源:临床与病理杂志 年份:2015
SOX2是在胚胎发育中发挥关键作用的干细胞转录因子,它是一组能使人类体细胞转化成多能干细胞的因子(Oct4,SOX2,Nanog)的基因之一.SOX2的过度表达在各种肺癌组织类型如肺小细...
[期刊论文] 作者:Mariacarmela Santarpia,Niki Karachaliou,, 来源:Cancer Biology & Medicine 年份:2015
In recent years,further understanding of the interaction between the immune system and tumor growth has led to the development of several immunotherapies.These...
[期刊论文] 作者:Niki Karachaliou,Maria Gonzale, 来源:癌症生物学与医学(英文版) 年份:2015
AbstrAct Survival rates for metastatic lung cancer, including non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), are poor with 5-year surviva...
[期刊论文] 作者:Cristina Teixidó,Niki Karachaliou,Maria González-Cao,Daniela Morales-Espinosa,Rafael Rosell,, 来源:Cancer Biology & Medicine 年份:2015
Immunotherapy has become a key strategy for cancer treatment, and two immune checkpoints, namely, programmed cell death 1(PD-1) and its ligand(PD-L1), have rece...
[期刊论文] 作者:Cristina Teixidó,Niki Karachaliou,Maria González-Cao,Daniela Morales-Espinosa,Rafael Rosell,, 来源:Cancer Biology & Medicine 年份:2015
In the published article1,one error appeared on page 89.Pembrolizumab has not yet received FDA approval for NSCLC patients.In October 2014 pembrolizumab receive...
[期刊论文] 作者:María Gonzalez-Cao,Paola Iduma,Niki Karachaliou,Mariacarmela Santarpia,Julià Blanco,Rafael Rosell,, 来源:Cancer Biology & Medicine 年份:2016
Human endogenous retroviruses(HERVs) are retroviruses that infected human genome millions of years ago and have persisted throughout human evolution. About 8% o...
[期刊论文] 作者:Niki Karachaliou,Maria Gonzalez Cao,Cristina Teixidó,Santiago Viteri,Daniela Morales-Espinosa,Mariacarmela, 来源:Cancer Biology & Medicine 年份:2015
Survival rates for metastatic lung cancer, including non-small cell lung cancer(NSCLC) and small cell lung cancer(SCLC), are poor with 5-year survivals of less...
[期刊论文] 作者:Cristina Teixidó,Niki Karachaliou,Vicente Peg,Ana Gimenez-Capitan,Rafael Rosell,魏建国,许春伟,张博,, 来源:临床与病理杂志 年份:2015
棘皮动物微管结合蛋白-间变性淋巴瘤激酶(echinoderm microtubule-associated prote i n-l ike4-anaplastic lymphoma kinase,EML4-ALK)在肺癌中已成为第二个最重要的驱动致...
[期刊论文] 作者:Jean G.Bustamante Alvarez,María González-Cao,Niki Karachaliou,Mariacarmela Santarpia,Santiago Viteri,, 来源:Cancer Biology & Medicine 年份:2015
Different approaches for treating lung cancer have been developed over time, including chemotherapy, radiotherapy and targeted therapies against activating muta...
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